7-test panel✓ COA verified ILS LaboratoriesPurity, Identity, Content +4Purity, Identity, Content, Endotoxin, Heavy metals, Sterility, Fentanyl screenView COA
7-test panel✓ COA verified ILS LaboratoriesPurity, Identity, Content +4Purity, Identity, Content, Endotoxin, Heavy metals, Sterility, Fentanyl screenView COA
7-test panel✓ COA verified ILS LaboratoriesPurity, Identity, Content +4Purity, Identity, Content, Endotoxin, Heavy metals, Sterility, Fentanyl screenView COA
7-test panel✓ COA verified ILS LaboratoriesPurity, Identity, Content +4Purity, Identity, Content, Endotoxin, Heavy metals, Sterility, Fentanyl screenView COA
5-test panelView COA Vanguard LaboratoryPurity, Content, Endotoxin +2Purity, Content, Endotoxin, Heavy metals, SterilityNot verified: lab has no verification record
8-test panel✓ COA verified Optiq Health LabsPurity, Identity, Content +5Purity, Identity, Content, Endotoxin, Heavy metals, Sterility, Residual solvents, pHView COA
5-test panelView COA Vanguard LaboratoryPurity, Content, Endotoxin +2Purity, Content, Endotoxin, Heavy metals, SterilityNot verified: lab has no verification record
$61.99🏷️5% off via our link·auto10mg packageChecked
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded. COA coverage counts vendors with an exact compound-and-strength match in the listing-evidence projection; report dates and lot identifiers remain specific to each certificate.
Compare current Selank prices and matching laboratory evidence.
Checked through
The lowest current 10mg cost for Selank is $15.39 from Arkon Labs Research. The median across vendors is $39.60.
Lowest 10mg cost
$15.39Arkon Labs Research
Median 10mg cost
$39.60One normalized offer per vendor
Lowest package total
$13.50Luv Aminos · package size may differ
Vendors with matching verified COAs
121of 201 vendors · Selank
What the market shows
PeptidePrices found 232 in-stock listings from 201 vendors, checked through Oct 30, 2026. The lowest 10mg cost is 61% below the vendor median of $39.60; 100 vendors (50%) fall below that median. 121 of 201 vendors (60%) have an exact issuer-verified COA for at least one listed Selank strength.
Selank is a synthetic seven-amino-acid peptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) built from the immunopeptide tuftsin with a Pro-Gly-Pro extension [4]. It is registered in Russia as a 0.15% nasal-drop anxiolytic, and Russian trials have compared it with benzodiazepines in generalized anxiety disorder, neurasthenia, and mixed anxiety disorders [6][1][2].
Those studies are small and largely single-center, with limited reporting of randomization and blinding, and there is no FDA approval. Claims about memory or focus in healthy people go beyond the published human evidence. N-Acetyl Selank Amidate and Selank Spray are separate catalog products with no direct trials identified here.
Key takeaways
A 62-patient comparison found Selank and medazepam produced similar anxiolytic effects, while Selank also showed antiasthenic and psychostimulant effects and raised the half-life of leu-enkephalin in generalized anxiety disorder [1].
A 70-patient add-on study reported that Selank plus phenazepam improved depressive symptoms earlier and reduced several benzodiazepine side effects, including attention and memory complaints, sedation, and asthenia [2].
Rat studies show rapid changes in GABAergic neurotransmission genes and prevention of alcohol-related memory impairment with normalized hippocampal BDNF, but these are not human cognitive outcomes [3][4].
How it works
Indirect modulation of the GABAergic system
Selank is a tuftsin analogue with a Pro-Gly-Pro tail. Laboratory work supports an indirect GABAergic effect rather than direct receptor agonism: in rat frontal cortex, Selank changed the expression of 45 neurotransmission-related genes at one hour and 22 at three hours, with a pattern that correlated with GABA administration, and the authors proposed allosteric modulation of the GABAergic system [3].
Enkephalin and BDNF pathways
Selank also inhibits enkephalin-degrading enzymes in human serum in vitro, which could extend enkephalin signaling, and it regulates hippocampal BDNF after intranasal dosing in rats [5][4]. These findings describe plausible pathways; they do not identify a single receptor or prove that the same pathway produces clinical anxiolysis.
What has been studied in humans
In a 62-patient study of generalized anxiety disorder and neurasthenia, 30 patients received Selank and 32 received medazepam [1]. Both drugs reduced anxiety on the Hamilton, Zung, and CGI scales to a similar degree, but Selank also produced antiasthenic and psychostimulant effects. Patients with generalized anxiety disorder had reduced leu-enkephalin half-life at baseline, and Selank treatment increased it, with stronger correlations to anxiety improvement in that subgroup [1]. A separate 70-patient study compared phenazepam alone in 30 patients with Selank plus phenazepam in 40 patients; the combination produced earlier improvement on the Hamilton Depression Rating Scale and reduced benzodiazepine-related attention and memory impairment, asthenia, sedation, sleep prolongation, and emotional indifference during treatment and after withdrawal, with better quality-of-life scores [2]. Neither report describes a placebo arm, and randomization and blinding are not clear from the accessible abstracts. No human study of healthy cognitive enhancement was identified. The Russian registration covers a 0.15% nasal-drop medicine, not the acetylated amidate or spray [6].
Lab and animal studies
In rats, Selank changed frontal-cortex expression of genes involved in GABA receptor subunits, transporters, ion channels, and dopamine and serotonin receptors, with partial overlap with GABA's own transcriptional effect [3]. In outbred rats given 10% ethanol for 30 weeks, seven days of Selank prevented ethanol-withdrawal memory and attention deficits in an object-recognition test and prevented the ethanol-induced rise in BDNF in hippocampus and frontal cortex [4]. Other rodent work reports anxiolytic-like effects, modulation of enkephalin degradation, and changes in serotonin and dopamine metabolites. These models support a plausible mechanism but use drug exposure and behavioral tasks that do not map directly onto human anxiety or cognition.
Comparative clinical study; Selank versus medazepam; psychometric scales plus serum enkephalinase activity · 62 patients with generalized anxiety disorder and neurasthenia (30 Selank, 32 medazepam)
Anxiolytic effects were similar between groups, but Selank also showed antiasthenic and psychostimulant effects; Selank increased leu-enkephalin half-life, especially in generalized anxiety disorder.
Evidence scope: Small single-country study, no placebo, and randomization and blinding are not described in the accessible abstract.
Comparative clinical study; phenazepam monotherapy versus Selank plus phenazepam, with HDRS, CGI, Spielberger, UKU side-effect, Stroop, verbal-fluency, and SF-36 measures · 70 patients with anxiety-phobic, hypochondriac, or somatoform disorders (30 phenazepam alone, 40 combination)
The combination produced earlier improvement on the Hamilton Depression Rating Scale and reduced benzodiazepine side effects, including attention and memory impairment, asthenia, sedation, and orthostasis, with better quality of life.
Evidence scope: Open-label add-on design; the additional benefit cannot be separated from extra clinical contact or expectancy.
Controlled rat experiment with frontal-cortex gene-expression profiling at one and three hours after Selank or GABA · Rats
Selank changed 45 neurotransmission-related genes at one hour and 22 at three hours, with a pattern that correlated with GABA administration, supporting an allosteric GABAergic mechanism.
Evidence scope: Transcriptional changes in rat cortex do not establish receptor binding, circuit-level anxiolysis, or human benefit.
Controlled rat experiment with 30 weeks of 10% ethanol exposure, seven days of Selank, object-recognition testing, and ex vivo BDNF measurement · Outbred rats
Selank prevented ethanol-induced memory and attention disturbances during withdrawal and prevented the ethanol-induced increase in BDNF in hippocampus and frontal cortex.
Evidence scope: Animal model of chronic alcohol exposure; memory tasks and BDNF changes are not direct evidence of human cognition.
The future: what's next for Selank
Whether the anxiolytic effect survives a double-blind, placebo-controlled design, since the existing comparisons are small and mostly open-label [1][2].
Whether the reported reduction in benzodiazepine side effects reflects a true pharmacodynamic interaction or a difference in co-prescribing and assessment [2].
Whether any cognitive benefit exists independently of anxiety reduction, and whether the acetylated amidate or spray forms produce comparable brain exposure.
Price, research & COA
Quick answers about Selank
Price answers use the live price, vendor, and certificate data on this page. Research answers cite the numbered sources below.
What is the cheapest Selank listing?
Arkon Labs Research has the lowest 10mg listing at $15.39, checked October 30, 2026.
You can view the cheapest prices for other strengths and sizes in the table directly below.
Cheapest in-stock listing by strength
Strength
Vendor
Price
Checked
5mg
Luv Aminos
$13.50
October 15, 2026
10mg
Arkon Labs Research
$15.39
October 30, 2026
20mg
BioPoint Peptides
$54.00
October 18, 2026
30mg
Novaglo Research
$58.50
October 23, 2026
50mg
Trulife Peptides
$116.00
October 30, 2026
100mg
Trulife Peptides
$184.00
October 30, 2026
Prices apply known public coupon codes; shipping and tax are not included.
PeptidePrices currently compares 201 tracked vendors for Selank. The median 10mg price is $38.25, checked on October 30, 2026, from a sample of 177 vendors.
You can view the median cost for other strengths and sizes beneath.
Median in-stock price by strength
Strength
Median
Vendors
Price range
5mg
$29.75
41
$13.50 to $51.99
10mg
$38.25
177
$15.39 to $109.99
20mg
$79.63
2
$54.00 to $105.26
30mg
$80.99
7
$58.50 to $157.88
50mg
Single listing
1
$116.00
100mg
Single listing
1
$184.00
Prices apply known public coupon codes; shipping and tax are not included.
No single vendor is best for every researcher. Compare Selank vendors on total cost, PeptidePrices quality rating, attached COA evidence, payment options, shipping, and how recently the listing was checked. We encourage researchers to read through our vendor reviews and inspect the attached COAs before making a decision. You can review our methodology here.
Should I pick a Selank vendor with a COA?
Yes. The PeptidePrices editorial team generally recommends that researchers only purchase from vendors with COAs attached to their Selank listing. If a vendor with a COA doesn't meet all of your buying needs, that's all right: Selank currently has 121 vendors with an in-stock listing that carries a matched COA. Without leaving this page, you can open each matched certificate PDF in the on-page viewer and see the issuing laboratory, report date and test panel. You can also read our independent analysis of purity, content, identity, endotoxin and the other panels, then follow the link to verify the certificate on the lab's own record.
How do I find the cheapest Selank for the size I want?
The comparison table lists all 201 tracked vendors for Selank, sorted by price. Use Size to compare one or more vial strengths, Ships to for the US, Canada, the UK, Australia, the EU or international destinations, and Payment method for credit or debit card, ACH or bank transfer, Zelle, Cash App, Venmo, PayPal, Apple Pay, cryptocurrency or Interac e-Transfer.
A vendor's certificate of analysis is attached to its listing when it matches the exact compound, strength and unit. 121 of the 201 vendors currently have an issuer-verified certificate attached. Open it to read the full certificate in an on-page viewer you can zoom, with our summary of the reported results beside it: purity, content and identity, plus endotoxin, sterility, heavy metals and fentanyl screens when the vendor had them tested. To check it yourself, follow the link to the laboratory's own verification record, where the laboratory publishes one, and to the original certificate on the vendor's site.
Yes, in small Russian comparative trials in patients with anxiety disorders. In a 62-patient study, Selank and medazepam reduced anxiety to a similar degree, and Selank also showed antiasthenic and psychostimulant effects [1]. In a 70-patient study, adding Selank to phenazepam produced earlier improvement on the Hamilton Depression Rating Scale and fewer benzodiazepine side effects [2]. Neither report describes a placebo arm, and no human study of cognitive enhancement in healthy adults has been identified.
Is Selank FDA approved?
No, Selank has no FDA approval. It is registered in Russia as a 0.15% nasal-drop anxiolytic [6]. That registration and the Russian trial data apply to the parent nasal-drop product, not to the N-Acetyl Selank Amidate or Selank Spray listings [6].
How does Selank work?
Laboratory work points to an indirect effect on the GABAergic system rather than direct receptor agonism. In rat frontal cortex, Selank changed the expression of 45 neurotransmission-related genes at one hour, in a pattern that correlated with GABA administration [3]. It also inhibits enkephalin-degrading enzymes in human serum in vitro and regulates hippocampal BDNF in rats [5][4]. No single receptor target has been identified, and it is not proven that these pathways produce anxiety relief in humans.
