DSIP (Delta Sleep-Inducing Peptide)Circadian PeptideSafety Rating 6/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Price Comparison
Compare vendors · per 5mg
| Vendor | Price | $ / mg | Updated | |
|---|---|---|---|---|
| Puratek PeptidesBest $/mgCOA ✓ · 3P | $28.30 | $2.83 | May 19, 2026 | Buy → |
| Ascension PeptidesCOA ✓ · 3P | $37.50 | $3.75 | Apr 16, 2026 | Buy → |
| Amino ClubCOA ✓ · 3P | $23.99 | $4.80 | May 14, 2026 | Buy → |
| Polar PeptidesCOA on request | $89.99 | $6.00 | Apr 17, 2026 | Buy → |
| Vantyx ResearchCOA on request | $90.00 | $6.00 | Apr 13, 2026 | Buy → |
Overview
About DSIP
Mechanism of action
Neuropeptide that crosses the blood-brain barrier; modulates GHRH, somatostatin, and LH secretion; reduces somatostatin activity; promotes slow-wave (delta) sleep.
Safety profile
Generally well-tolerated. Occasional headache, slight fatigue post-injection. Long-term data limited. · Human studies from 1980s–90s showed tolerability; no major adverse events reported; limited modern data
Storage
Stability & handling
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Safety & Interactions
Contraindications & Drug Interactions
Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.
Limited modern clinical data; 1980s-90s studies showed good tolerability.
Sedatives, benzodiazepines, alcohol — theoretical additive CNS depression.
Related pages
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Research
Studies & key findings
- Originally isolated from rabbit cerebral venous blood during slow-wave sleep (Monnier et al., 1977), DSIP is one of the first peptides identified as a sleep regulator.
- Beyond sleep induction, has demonstrated analgesic properties in chronic pain models, stress-protective effects, and benefit in alcohol and opiate withdrawal syndromes.