SemaxCognitive & Neuroprotective PeptideSafety Rating 8/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Price Comparison
Compare vendors · per 10mg
| Vendor | Price | $ / mg | Updated | |
|---|---|---|---|---|
| Deus MedicalBest $/mgCOA on requestOut of stock | $16.20 | $1.62 | Apr 17, 2026 | Buy → |
| Polar PeptidesCOA on request | $57.59 | $1.92 | Apr 17, 2026 | Buy → |
| Biotech PeptidesCOA unknown | $53.00 | $2.12 | May 14, 2026 | Buy → |
| Amino ClubCOA ✓ · 3P | $23.99 | $2.40 | May 14, 2026 | Buy → |
| Swiss ChemsCOA ✓ · 3P | $73.95 | $2.47 | Apr 17, 2026 | Buy → $25 off $100+·auto |
Overview
About Semax
Mechanism of action
Synthetic analogue of ACTH(4-7); increases BDNF and NGF expression; modulates dopaminergic and serotonergic systems; neuroprotective; enhances memory consolidation.
Safety profile
Very well-tolerated. Occasional nasal irritation, fatigue, or overstimulation. Mild dopaminergic effects. · Approved for neurological conditions in Russia; intranasal well-tolerated; no major safety signals
Storage
Stability & handling
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Safety & Interactions
Contraindications & Drug Interactions
Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.
Russian clinical use for stroke/TBI. No significant contraindications reported but Western clinical data is limited.
Related pages
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Semax Guide
A research guide to Semax — the nootropic peptide developed in Russia.
Read full guide · 8 min read →Research
Studies & key findings
- ACTH(4-7)-Pro-Gly-Pro heptapeptide with nootropic and neuroprotective properties; approved in Russia for ischemic stroke and cognitive disorders, delivered intranasally.
- Potently upregulates BDNF, TrkB, and NGF expression in rat hippocampus — the mechanistic basis for cognitive-enhancing and neuroprotective effects.