Cognitive & Neuroprotective Peptide

Semax

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VendorPrice10mg costUpdatedActions
Alpha Peptides8/10
8/10
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8/10
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$20.84$23.16−10% · code PEPTIDEPRICES1010mg package$20.84Checked jul 31, 2026Jul 31, 2026Buy Semax from Alpha Peptides
TrustedPeps8.5/10
8.5/10
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8.5/10
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$22.50$25.00−10% · code peptideprices10mg package$22.50Checked aug 1, 2026Aug 1, 2026Buy Semax from TrustedPeps
Amino Club10/10
10/10
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10/10
COA ✓Ships: US + internationalVisa · Mastercard
$22.74$34.99−35% · code PEPTIDEPRICES10mg package$22.74Checked aug 7, 2026Aug 7, 2026Buy Semax from Amino Club
Pure Amino7/10
7/10
COA ✓Ships: USCredit/debit card · Supported digital wallets
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7/10
COA ✓Ships: USCredit/debit card · Supported digital wallets
$23.99$29.99−20% · code PEPTIDEPRICES10mg package$23.99Checked aug 15, 2026Aug 15, 2026Buy Semax from Pure Amino
Cielo Peptides6/10
6/10
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6/10
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$24.00$30.00−20% · code PEPTIDEPRICES11mg package$24.00Checked aug 8, 2026Aug 8, 2026Buy Semax from Cielo Peptides
Peptyx Labs8.5/10
8.5/10
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8.5/10
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$24.00$30.00−20% · code PEPTIDEPRICES2510mg package$24.00Checked may 26, 2026May 26, 2026Buy Semax from Peptyx Labs

Research details

Semax — research data

Half-life~3 hours; intranasal preferred. Daily dosing.
Regulatory statusApproved in Russia/Ukraine
NCAA D1Not listed

Overview

About Semax

Mechanism of action

Synthetic analogue of ACTH(4-7); increases BDNF and NGF expression; modulates dopaminergic and serotonergic systems; neuroprotective; enhances memory consolidation.

Safety profile

Very well-tolerated. Occasional nasal irritation, fatigue, or overstimulation. Mild dopaminergic effects. · Approved for neurological conditions in Russia; intranasal well-tolerated; no major safety signals

Storage

Stability & handling

❄️Lyophilized (powder)−20°Cprotect from light
💉Reconstituted2–8°Cwithin 4 weeks

Safety & Interactions

Contraindications & Drug Interactions

Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.

ℹ NoteCaution

Russian clinical use for stroke/TBI. No significant contraindications reported but Western clinical data is limited.

Related pages

More on Semax

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Research

Studies & key findings

  • ACTH(4-7)-Pro-Gly-Pro heptapeptide with nootropic and neuroprotective properties; approved in Russia for ischemic stroke and cognitive disorders, delivered intranasally.
  • Potently upregulates BDNF, TrkB, and NGF expression in rat hippocampus — the mechanistic basis for cognitive-enhancing and neuroprotective effects.

7 peer-reviewed sources cited — clinical, preclinical, and regulatory.

Read full research →
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