Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro, MW ≈ 813.9 g/mol) built from the ACTH(4-7) fragment plus a stabilizing Pro-Gly-Pro tail, developed in 1982 in Russia for neuroprotection and cognitive enhancement.
Semax Prices
168 vendors · 98 with an issuer-verified COA · lowest 10mg from $18.49 · checked
Where to buy Semax: 168 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| 2-test panelVerified COAJanoshik · Tested Aug 21, 2026 | $18.4910mg packageChecked today | Buy Semax from Corix Labs |
| 2-test panelCOA on fileVanguard Laboratory · Tested Dec 31, 2025 | $20.00 | Buy Semax from Pepvida Labs |
| 3-test panelVerified COAFreedom Diagnostics · Tested Oct 2, 2026 | $21.59 | Buy Semax from Molecula Labs |
| 2-test panelCOA on fileVanguard Laboratory · Tested May 13, 2026 | $21.68 | Buy Semax from Precisely Peptides |
| 6-test panelVerified COAKovera Labs | $21.88 | Buy Semax from Alpha Peptides |
| 4-test panelVerified COASteriGenix Analytical · Tested Jul 28, 2026 | $22.31 | Buy Semax from Studz Peptides |
| 1-test panelVerified COAILS Laboratories | $22.46 | Buy Semax from Amino Club |
| 3-test panelVerified COAFreedom Diagnostics · Tested May 8, 2026 | $22.49 | Buy Semax from IDUN Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Apr 5, 2026 | $22.50 | Buy Semax from TrustedPeps |
| 7-test panelVerified COAILS Laboratories · Tested Aug 11, 2026 | $22.79 | Buy Semax from ZC Labs |
| $23.40 | Buy Semax from Ararat Peptides | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Jun 8, 2026 | $23.99 | Buy Semax from Everest Peptides |
| 7-test panelVerified COAILS Laboratories · Tested Jul 13, 2026 | $23.99 | Buy Semax from Pure Amino |
| 2-test panelCOA on fileVanguard Laboratory · Tested Mar 30, 2026 | $24.00 | Buy Semax from Cielo Peptides |
| $24.55 | Buy Semax from Red River Peptides | |
| 5-test panelVerified COAKovera Labs · Tested Jul 24, 2026 | $24.70 | Buy Semax from RetaOne Labs |
| 5-test panelVerified COAKovera Labs · Tested Jun 23, 2026 | $25.00 | Buy Semax from Ascension Peptides |
| $25.19 | Buy Semax from T-Core Biotech | |
| 3-test panelVerified COABioViridian | $25.20 | Buy Semax from P3 Labs |
| 7-test panelVerified COAILS Laboratories · Tested Jul 16, 2026 | $25.49 | Buy Semax from Aigil Research |
| 7-test panelVerified COAILS Laboratories · Tested Aug 20, 2026 | $25.49 | Buy Semax from Orbitrex Peptides |
| 7-test panelVerified COAFreedom Diagnostics · Tested Jul 25, 2026 | $26.24 | Buy Semax from Modern Research Peptides |
| $26.25 | Buy Semax from Atomik Labz | |
| 6-test panelVerified COAJanoshik · Tested Feb 19, 2026 | $26.25 | Buy Semax from Hydro Research |
| 3-test panelVerified COAFreedom Diagnostics · Tested May 8, 2026 | $26.25 | Buy Semax from Rocky Mountain Compounds |
| $26.39 | Buy Semax from Arctic Lab Supply | |
| 4-test panelVerified COAHorizon Analytical · Tested Sep 13, 2026 | $26.99 | Buy Semax from Averix Labs |
| $26.99 | Buy Semax from Midwest Peptide | |
| 3-test panelVerified COABT Labs | $26.99 | Buy Semax from Summit Pep Labs |
| 4-test panelVerified COAHorizon Analytical · Tested Aug 19, 2026 | $26.99 | Buy Semax from Summit Research Supply |
| 4-test panelVerified COAFreedom Diagnostics · Tested Aug 23, 2026 | $26.99 | Buy Semax from VoidResearch |
| $26.99 | Buy Semax from Woosh Labs | |
| 3-test panelVerified COAFreedom Diagnostics · Tested May 17, 2026 | $26.99 | Buy Semax from Y&P Labs |
| 7-test panelVerified COAKovera Labs · Tested Jun 1, 2026 | $27.00 | Buy Semax from Avara |
| 7-test panelVerified COAFreedom Diagnostics · Tested Sep 23, 2026 | $27.00 | Buy Semax from Lost Coast Aminos |
| 3-test panelVerified COAFreedom Diagnostics | $27.00 | Buy Semax from Novaglo Research |
| 7-test panelVerified COAKovera Labs · Tested Jul 15, 2026 | $27.67 | Buy Semax from Glacier Aminos |
| 3-test panelVerified COAKovera Labs · Tested Sep 2, 2026 | $27.90 | Buy Semax from Vector Amino Labs |
| 2-test panelCOA on fileVanguard Laboratory · Tested Aug 13, 2025 | $27.99 | Buy Semax from Vital Core Research |
| 3-test panelVerified COAFreedom Diagnostics · Tested May 3, 2026 | $28.50 | Buy Semax from Elytra Labs |
| $28.79 | Buy Semax from RUO Market | |
| $28.89 | Buy Semax from Durham Peptides | |
| $29.37 | Buy Semax from Anglo Peptides | |
| $29.66 | Buy Semax from Puratek Peptides | |
| 6-test panelVerified COAKovera Labs · Tested Apr 26, 2026 | $29.70 | Buy Semax from RemedyX Labs |
| Verified COASteriGenix Analytical | $29.74 | Buy Semax from Purgo Labs |
| 5-test panelVerified COAJanoshik · Tested Mar 3, 2026 | $29.75 | Buy Semax from Optima Supply |
| 2-test panelVerified COAOptima Labs | $29.9910mg packageChecked today | Buy Semax from Peptides Lab UK |
| 6-test panelVerified COAILS Laboratories · Tested Aug 11, 2026 | $29.9910mg packageChecked Oct 5 | Buy Semax from Vortex Research |
| 3-test panelVerified COASideChain Analytics | $30.65 | Buy Semax from Vistara Labs |
| $30.86 | Buy Semax from Panda Peptide | |
| 6-test panelVerified COALiquilabs | $31.4410mg packageChecked today | Buy Semax from Particle Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested May 8, 2026 | $31.44 | Buy Semax from Synthesis Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Jun 30, 2026 | $31.46 | Buy Semax from Zen Aminos |
| 3-test panelVerified COAFreedom Diagnostics · Tested Sep 15, 2026 | $31.49 | Buy Semax from HLX Labs |
| $31.49 | Buy Semax from Optimum Formula | |
| $31.50 | Buy Semax from American Amino & Peptides | |
| 3-test panelCOA on fileBT Labs · Tested Jul 6, 2026 | $31.50 | Buy Semax from BioLeno |
| 8-test panelVerified COAKovera Labs | $31.50 | Buy Semax from Ivory Labs |
| 6-test panelVerified COAILS Laboratories · Tested Aug 18, 2026 | $31.50 | Buy Semax from NextGen Peptides |
| 3-test panelCOA on fileNorthPeak Analytical · Tested Sep 10, 2026 | $31.64 | Buy Semax from Peptide Bros Canada |
| $31.92 | Buy Semax from ORA Labs | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Jul 13, 2026 | $31.99 | Buy Semax from Global Aminos |
| 4-test panelVerified COAKovera Labs · Tested May 19, 2026 | $31.99 | Buy Semax from PuraSynth Labs |
| 3-test panelVerified COAFreedom Diagnostics | $32.39 | Buy Semax from GMR Peptides |
| 6-test panelVerified COAProof Point Analytical · Tested Sep 22, 2026 | $32.39 | Buy Semax from Prism Labs |
| Verified COAChromate | $32.40 | Buy Semax from Pantheon Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Sep 4, 2026 | $33.15 | Buy Semax from Peptide Maxxing |
| 2-test panelVerified COAJanoshik · Tested Jun 24, 2026 | $33.6110mg packageChecked today | Buy Semax from Omega Peptides |
| 3-test panelVerified COABTLabs · Tested Jun 18, 2026 | $33.75 | Buy Semax from RNX Research |
| 2-test panelVerified COAHorizon Analytical · Tested Apr 30, 2026 | $33.99 | Buy Semax from EZ Peps |
| $33.99 | Buy Semax from PepMarket | |
| $34.00 | Buy Semax from Vantyx Research | |
| $34.20 | Buy Semax from Peptide Giants | |
| 4-test panelVerified COAFreedom Diagnostics · Tested Aug 11, 2026 | $34.65 | Buy Semax from Sorex Labs |
| $35.0010mg packageChecked today | Buy Semax from Pro Research Peptide | |
| $35.0810mg packageChecked today | Buy Semax from Pure Peptide | |
| $35.10 | Buy Semax from Elevate Research Labs | |
| 3-test panelVerified COAKovera Labs · Tested Sep 29, 2026 | $35.10 | Buy Semax from LabFirst Peptides |
| $35.10 | Buy Semax from Noble Sciences | |
| $35.19 | Buy Semax from Cenexa Labs | |
| 4-test panelVerified COAFreedom Diagnostics | $35.36 | Buy Semax from PeakForce Labs |
| $35.99 | Buy Semax from Arizen Bio Labs | |
| $35.99 | Buy Semax from MS Peptides | |
| $35.99 | Buy Semax from Prime Peptide Solutions | |
| $35.99 | Buy Semax from Qureshi Labs | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Sep 2, 2026 | $35.99 | Buy Semax from Rebirth Labs |
| 3-test panelVerified COAFreedom Diagnostics | $35.99 | Buy Semax from Thrive Peptides |
| 7-test panelVerified COAILS Laboratories · Tested Aug 11, 2026 | $36.00 | Buy Semax from Ascending Labs |
| 7-test panelVerified COAKovera Labs · Tested Aug 18, 2026 | $36.00 | Buy Semax from Forge Performance Co. |
| $36.00 | Buy Semax from Genix Peps | |
| $36.79 | Buy Semax from Amino Science Labs | |
| $37.67 | Buy Semax from PhaseOne AUS | |
| $38.24 | Buy Semax from Rivn Peptides | |
| 5-test panelVerified COAFreedom Diagnostics · Tested Jun 14, 2026 | $38.25 | Buy Semax from Nura Peptide |
| 7-test panelVerified COAKovera Labs | $39.16 | Buy Semax from NeuroLabs |
| $39.99 | Buy Semax from Evo Labs Research | |
| $40.0010mg packageChecked today | Buy Semax from Ignite Peptides | |
| 2-test panelVerified COAJanoshik | $40.40 | Buy Semax from CertaPeptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Sep 4, 2025 | $40.50 | Buy Semax from Athena Peptides |
| 1-test panelVerified COAPrime Analytical Laboratories | $40.50 | Buy Semax from Pepsynth Labs |
| 3-test panelVerified COAJanoshik · Tested Dec 4, 2024 | $40.80 | Buy Semax from Happy Peptides |
| 4-test panelVerified COAKovera Labs · Tested Sep 4, 2026 | $41.30 | Buy Semax from Axovera Labs |
| 3-test panelVerified COAFreedom Diagnostics | $41.39 | Buy Semax from Fit Aminos |
| $41.65 | Buy Semax from Apex Peptides Lab | |
| 3-test panelVerified COAJanoshik · Tested Jun 22, 2026 | $41.65 | Buy Semax from Honest Peptide |
| 3-test panelVerified COAJanoshik · Tested Jun 19, 2026 | $42.0010mg packageChecked today | Buy Semax from NextGenPeps |
| $42.49 | Buy Semax from Dual Aminos | |
| 6-test panelVerified COAILS Laboratories · Tested Jun 29, 2026 | $42.49 | Buy Semax from Voltera Sciences |
| $42.50 | Buy Semax from Evolve Peptides | |
| $42.50 | Buy Semax from Sparta Labs | |
| $44.0810mg packageChecked today | Buy Semax from Regenix Peptides | |
| $44.1610mg packageChecked today | Buy Semax from Optic Labs AU | |
| 4-test panelVerified COAFreedom Diagnostics · Tested Apr 23, 2026 | $44.99 | Buy Semax from Glow Peptides |
| 3-test panelVerified COAFreedom Diagnostics | $45.00 | Buy Semax from Axon Chems |
| 3-test panelVerified COAHorizon Analytical | $45.00 | Buy Semax from Blank Peptides |
| 7-test panelVerified COAKovera Labs | $45.00 | Buy Semax from Instant Peptides |
| 2-test panelVerified COAMZ BioLabs · Tested Nov 25, 2025 | $45.00 | Buy Semax from Nexa Labs |
| $45.0010mg packageChecked today | Buy Semax from PeakForm Peptides | |
| 7-test panelVerified COAMistral Diagnostics | $45.00 | Buy Semax from Peptide Express |
| 3-test panelVerified COAKovera Labs · Tested Jul 19, 2026 | $45.00 | Buy Semax from Peptoria |
| $45.74 | Buy Semax from Swift Peptides | |
| $46.63 | Buy Semax from Nova Labs | |
| $46.75 | Buy Semax from HEEZ Research | |
| 2-test panelCOA on fileHorizon Analytical · Tested Apr 17, 2026 | $46.75 | Buy Semax from Impact Aminos |
| 3-test panelVerified COAFreedom Diagnostics · Tested Aug 20, 2026 | $48.00 | Buy Semax from Veragen Labs |
| $48.9910mg packageChecked today | Buy Semax from Legion Peptides | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Mar 20, 2026 | $49.50 | Buy Semax from Great Northern Peptides |
| 3-test panelVerified COAChromate · Tested Mar 24, 2026 | $49.50 | Buy Semax from Origin Research |
| $50.0010mg packageChecked today | Buy Semax from Pristine Aminos | |
| 3-test panelVerified COAKovera Labs · Tested Aug 13, 2026 | $50.0010mg packageChecked today | Buy Semax from Pure Peptides |
| 3-test panelVerified COALiquilabs · Tested May 28, 2026 | $50.1510mg packageChecked Oct 7 | Buy Semax from Adria Science |
| $50.782 × 5mg packages · 10mg totalChecked today | Buy Semax from Pure Peptides UK | |
| 4-test panelVerified COAFreedom Diagnostics · Tested Jul 21, 2026 | $52.25 | Buy Semax from Iaso BioLabs |
| $53.0010mg packageChecked today | Buy Semax from Apex Compounds | |
| 4-test panelVerified COAHorizon Analytical · Tested Jul 19, 2026 | $53.10 | Buy Semax from Nurish Labs |
| 3-test panelCOA on fileAccurate Test Labs | $54.00 | Buy Semax from Eon Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Jun 1, 2026 | $54.00 | Buy Semax from UNYX Peptides |
| $54.00 | Buy Semax from Upgrade Bio Labs | |
| 2-test panelVerified COAJanoshik · Tested Aug 20, 2026 | $57.75 | Buy Semax from Atlas Longevity |
| $58.49 | Buy Semax from SKO Compounds | |
| 2-test panelVerified COAJanoshik · Tested Jul 14, 2026 | $58.49 | Buy Semax from ZestyRat Research |
| 3-test panelVerified COABioViridian | $58.50 | Buy Semax from American Peptides |
| 3-test panelVerified COAFreedom Diagnostics · Tested Oct 10, 2025 | $59.48 | Buy Semax from SomaChems |
| $60.002 × 5mg packages · 10mg totalChecked today | Buy Semax from BioNova Peptides | |
| $60.25 | Buy Semax from Mr Peps | |
| $61.20 | Buy Semax from Dynotides | |
| 5-test panelVerified COAJanoshik · Tested Aug 26, 2026 | $62.7910mg packageChecked today | Buy Semax from Ultima Life |
| 2-test panelVerified COAJanoshik · Tested Apr 16, 2026 | $64.60 | Buy Semax from Paramount Peptides |
| $65.0010mg packageChecked Jul 31 | Buy Semax from Apex Peptides | |
| 2-test panelVerified COAFreedom Diagnostics | $66.60 | Buy Semax from Nationwide Peptides |
| 3-test panelVerified COAJanoshik · Tested May 25, 2026 | $66.842 × 5mg packages · 10mg totalChecked today | Buy Semax from Kensington Labs |
| 2-test panelVerified COATestides · Tested Feb 4, 2026 | $67.9910mg packageChecked today | Buy Semax from Cellugenix Peptides |
| $70.0010mg packageChecked today | Buy Semax from Alpha Carbon Labs | |
| Verified COAILS Laboratories | $70.30 | Buy Semax from Amino Vault |
| $71.10 | Buy Semax from Prime Bio Labs USA | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Aug 23, 2026 | $75.0010mg packageChecked today | Buy Semax from Elite RX Labs |
| 3-test panelVerified COAChromate | $76.80 | Buy Semax from VAYN |
| $80.002 × 5mg packages · 10mg totalChecked today | Buy Semax from StrikePoint Peptides | |
| 2-test panelCOA on fileAccurate Test Labs | $80.10 | Buy Semax from Vyal Labs |
| 3-test panelVerified COAHorizon Analytical · Tested May 12, 2026 | $80.9910mg packageChecked today | Buy Semax from Northline Labs |
| $81.00 | Buy Semax from Peptides Costa Rica | |
| $85.50 | Buy Semax from Palmetto Peptides | |
| $89.9030mg packageChecked today | Buy Semax from GLP-1 Research Lab | |
| 3-test panelVerified COAFreedom Diagnostics · Tested Apr 14, 2026 | $90.00 | Buy Semax from Kronos Peptides |
| $93.49 | Buy Semax from Purity Peptides | |
| 6-test panelVerified COAEthos Analytics · Tested Jun 18, 2026 | $109.9915% off, applied by our link·auto10mg packageChecked today | Buy Semax from PureBio Labs |
| $124.08 | Buy Semax from BergdorfBio |
Tracked every day
Semax listing prices, tracked daily
The five cheapest in-stock package prices for Semax on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$18.49
- 2nd cheapest$19.95
- 3rd cheapest$19.99
- 4th cheapest$20.80
- 5th cheapest$21.99
Vendors most often in the cheapest five
- ORA Labs22 days$19.950.0%
- Pro Research Peptide18 days$19.990.0%
- Modern Research Peptides16 days$21.990.0%
- Alpha Peptides14 days$21.88last seen Oct 2, 20260.0%
- IDUN Peptides11 days$24.99last seen Oct 7, 20260.0%
- PeakForce Labs5 days$20.80-5.5%
- Corix Labs3 days$18.490.0%
- Molecula Labs3 days$23.99last seen Oct 9, 20260.0%
Top 8 of 15 vendors that reached the cheapest five
Current market data
Semax Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Semax is $18.49 from Corix Labs. The median across vendors is $35.99.
- Lowest 10mg cost
- $18.49Corix Labs
- Median 10mg cost
- $35.99One normalized offer per vendor
- Lowest package total
- $15.96ORA Labs · package size may differ
- Public COA coverage
- 98%165 of 168 vendors
What the market shows
PeptidePrices found 195 in-stock listings from 168 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 49% below the vendor median of $35.99; 82 vendors (49%) fall below that median. 165 of 168 vendors (98%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Semax? Research, safety, and status
Semax is a synthetic seven-amino-acid peptide developed in Russia for neuroprotection and cognitive enhancement. It is derived from a fragment of adrenocorticotropic hormone (ACTH) but, by design, carries none of ACTH's hormonal effects, its activity is restricted to neurotrophic, neuroprotective, and immunomodulatory pathways.
It is one of the more scientifically substantiated peptides in the nootropic space, with a research record spanning genome-wide transcriptomics, proteomics, rodent behavioral models, and human clinical trials in stroke and cognitive disorders. It has been an approved prescription pharmaceutical in Russia for decades and was added to the Russian List of Vital and Essential Drugs in 2011.
Key research takeaways
Despite its ACTH origin it is devoid of hormonal activity, it does not raise cortisol or engage the HPA axis; its action is confined to neurotrophic, neuroprotective, and immunomodulatory pathways.
Its best-documented mechanism is potent upregulation of BDNF and NGF via the CREB→TrkB pathway, alongside dopaminergic/serotonergic modulation (sensitization rather than direct flooding) and transcriptomic-level suppression of neuroinflammation after ischemia.
Evidence is more substantial than most nootropic peptides, genome-wide transcriptomics, proteomics, and human stroke/cognitive trials, but is concentrated in Russian institutions and journals, with no large Western replication.
Semax at a glance
PeptidePrices safety rating
8/10 · Approved in Russia/Ukraine
Mechanism
Synthetic analogue of ACTH(4-7); increases BDNF and NGF expression; modulates dopaminergic and serotonergic systems; neuroprotective; enhances memory consolidation.
Research areas
Cognitive enhancement (memory, focus, learning); neuroprotection; stroke recovery; ADHD; depression; anxiety; ischemic brain injury.
Regulatory / research status
Research / preclinical only
Half-life
~3 hours; intranasal preferred.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Very well-tolerated. Occasional nasal irritation, fatigue, or overstimulation. Mild dopaminergic effects.
Approved for neurological conditions in Russia; intranasal well-tolerated; no major safety signals Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- ACTH(4-7)-Pro-Gly-Pro heptapeptide with nootropic and neuroprotective properties; approved in Russia for ischemic stroke and cognitive disorders, delivered intranasally.
- Potently upregulates BDNF, TrkB, and NGF expression in rat hippocampus, the mechanistic basis for cognitive-enhancing and neuroprotective effects.
- Genome-wide analysis in focal ischemia models revealed Semax modulates over 84 genes in immune and vascular pathways, explaining its multi-system neuroprotection.
Selected references
- Semax Regulates BDNF and TrkB Expression in Rat Hippocampus · Brain Research, 2006
- Semax Affects Genes Related to Immune and Vascular Systems in Focal Ischemia · BMC Genomics / PMC, 2014
- Efficacy of Semax in Ischemic Stroke Treatment · Zhurnal Nevrologii, 2018
- Dynamics of NGF and BDNF Expression Under Semax · Journal of Molecular Neuroscience, 2010
- Protective Properties of Semax at the Molecular Level · IJMS / PMC, 2020
- Semax Cognitive Vitality For Researchers · Alzheimer's Drug Discovery Foundation, 2020
Related pages