Thymosin Alpha 1 (Tα1) is a natural 28-amino-acid thymus peptide that modulates the immune system, it's the amino-terminal segment of prothymosin alpha, first isolated in 1977.
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Tracked every day
Thymosin Alpha-1 listing prices, tracked daily
The five cheapest in-stock package prices for Thymosin Alpha-1 on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$23.56
- 2nd cheapest$26.72
- 3rd cheapest$27.72
- 4th cheapest$32.00
- 5th cheapest$32.40
Vendors most often in the cheapest five
- CertaPeptides19 days$23.56+12.2%
- Kensington Labs18 days$26.720.0%
- Pantheon Peptides16 days$32.400.0%
- Ameano Peptides14 days$35.00last seen Oct 7, 20260.0%
- Alpha Pro Peptides11 days$29.99last seen Sep 29, 20260.0%
- Elite Edge Biotech8 days$33.00last seen Oct 2, 20260.0%
- Peptide Giants7 days$35.00last seen Oct 6, 20260.0%
- Novaglo Research4 days$32.000.0%
Top 8 of 12 vendors that reached the cheapest five
Current market data
Thymosin Alpha-1 Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Thymosin Alpha-1 is $26.06 from Zen Aminos. The median across vendors is $67.50.
- Lowest 10mg cost
- $26.06Zen Aminos
- Median 10mg cost
- $67.50One normalized offer per vendor
- Lowest package total
- $21.20CertaPeptides · package size may differ
- Public COA coverage
- 99%100 of 101 vendors
What the market shows
PeptidePrices found 122 in-stock listings from 101 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 61% below the vendor median of $67.50; 50 vendors (50%) fall below that median. 100 of 101 vendors (99%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Thymosin Alpha-1? Research, safety, and status
What makes it stand out from most research peptides: it has genuine pharmaceutical approval in much of the world (as Zadaxin) and a decades-deep clinical literature, so the framing here leans on real trial data. The honest counterweight is that its two biggest historical use cases have weakened: hepatitis (eclipsed by modern antivirals) and sepsis (a large 2025 Phase 3 trial found no benefit). It's still not FDA-approved. Everything below is research context, not medical advice.
Key research takeaways
It's unusual among immune compounds for being homeostatic: it can boost an underactive immune response AND dampen an overactive inflammatory one, rather than just stimulating.
It has the deepest real-world clinical track record of the immune peptides, the synthetic version (Zadaxin / thymalfasin) is approved in 35+ countries for hepatitis B/C and as a cancer adjuvant, though NOT by the US FDA.
Honest caveat: the definitive Phase 3 sepsis trial (TESTS, 1,106 patients, 2025) found NO mortality benefit (23.4% vs 24.1%, p=0.93), earlier positive sepsis signals didn't hold up. And its hepatitis use is now largely obsolete given >95%-effective direct-acting antivirals.
It is not FDA-approved, but unlike Thymosin Beta-4 it is NOT on the WADA Prohibited List (as of 2026), its immunomodulatory, non-tissue-growth mechanism has kept it off.
Thymosin Alpha-1 at a glance
PeptidePrices safety rating
8/10 · Approved in 30+ countries
Mechanism
Endogenous peptide derived from thymosin fraction 5; modulates T-cell differentiation and maturation; upregulates MHC class I expression; stimulates dendritic cells; potentiates NK cell activity.
Research areas
Immune system enhancement; chronic infections (hepatitis B/C); cancer immunotherapy adjunct; autoimmune conditions; vaccine potentiation; sepsis; COVID-19 (used in Asia).
Regulatory / research status
Research / preclinical only
Half-life
~2 hours.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Very well-tolerated. rare flu-like symptoms. Decades of safety data.
11,000+ patients in 30+ trials; well-tolerated; approved as Zadaxin globally; excellent safety record Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Endogenous 28-amino-acid peptide derived from prothymosin α; approved (Zadaxin) in 35+ countries for chronic hepatitis B, hepatitis C, and as an adjuvant in cancer immunotherapy.
- Phase 3 RCT in chronic HBV (1998) showed thymosin α1 plus interferon-α produced significantly higher seroconversion rates than interferon alone.
- Activates dendritic cell tryptophan catabolism and modulates the Treg/effector T-cell balance, providing mechanistic basis for its use in both infection and inflammatory conditions including COVID-19 sepsis.
- Important null result to weigh: the 2025 TESTS Phase 3 sepsis trial (n=1,106) failed to show a mortality benefit (23.4% vs 24.1% at 28 days, HR 0.97, p=0.82), tempering enthusiasm built on smaller positive trials and arguing against routine use in undifferentiated sepsis.
Selected references
- Thymosin Alpha 1: A Comprehensive Review of Its Mechanisms and Clinical Applications · World Journal of Virology / PMC, 2020
- Thymosin Alpha-1 in Chronic Hepatitis B: Randomized Controlled Trial · Hepatology, 1998
- Immune Modulation with Thymosin Alpha 1 in Infectious Disease and Cancer · Expert Opinion on Biological Therapy, 2016
- Thymosin α1 Activates Dendritic Cell Tryptophan Catabolism and Tolerogenic Pathways · Blood (ASH), 2006
- Zadaxin (Thymalfasin) Prescribing Information · RxList / Zadaxin, 2023
- Pharmacokinetics of Thymosin Alpha-1 After Subcutaneous Injection in Healthy Volunteers · Clinical Pharmacokinetics, 1999
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