Thymosin Alpha-1Cellular PeptideSafety Rating 8/10

TypeSynthetic acetylated polypeptide
CAS62304-98-7
MW3,108.3 g/mol
AAs28
Primary research areaImmune-modulation research

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range900 mcg–1.6 mg SC twice weekly. Standard course: 6 months. Acute immune support: 1.6 mg/day for 2 weeks.
AdministrationVaries
Safety8/10 · Approved in 30+ countries
NCAA D1Not listed

Price Comparison

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23 vendors competing

VendorPrice$ / mgUpdated
Ascension PeptidesBest $/mgCOA ✓ · 3P$37.50$75.00−50% · code peptidepri$3.75Apr 16, 2026Buy →
Optimum FormulaCOA ✓ · 3P$40.49$44.99−10% · code PEPTIDEPRICES$4.05May 14, 2026Buy →
Amino ClubCOA ✓ · 3P$31.99$39.99−20% · code PEPTIDEPRICES$6.40May 14, 2026Buy →
Polar PeptidesCOA on request$64.79$6.48Apr 17, 2026Buy →
PureRawzCOA ✓ · 3P$79.45$7.95May 14, 2026Buy →

Overview

About Thymosin Alpha-1

Mechanism of action

Endogenous peptide derived from thymosin fraction 5; modulates T-cell differentiation and maturation; upregulates MHC class I expression; stimulates dendritic cells; potentiates NK cell activity.

Safety profile

Very well-tolerated. Injection site reactions; rare flu-like symptoms. Decades of safety data. · 11,000+ patients in 30+ trials; well-tolerated; approved as Zadaxin globally; excellent safety record

Storage

Stability & handling

❄️Lyophilized (powder)2–8°Cstable long-term
💉Reconstituted2–8°Cwithin 30 days
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Research

Studies & key findings

  • Endogenous 28-amino-acid peptide derived from prothymosin α; approved (Zadaxin) in 35+ countries for chronic hepatitis B, hepatitis C, and as an adjuvant in cancer immunotherapy.
  • Phase 3 RCT in chronic HBV (1998) showed thymosin α1 plus interferon-α produced significantly higher seroconversion rates than interferon alone.

8 peer-reviewed sources cited — clinical, preclinical, and regulatory.

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