TB-500 is a synthetic version of the active region (the Ac-LKKTETQ sequence) of thymosin beta-4, a natural 43-amino-acid protein the body uses for tissue repair, cell migration, and wound healing.
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Tracked every day
TB-500 listing prices, tracked daily
The five cheapest in-stock package prices for TB-500 on each collected day, and the vendors that most often held those places.
Loading price history…
Current market data
TB-500 Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for TB-500 is $20.99 from PeakForce Labs. The median across vendors is $53.99.
- Lowest 10mg cost
- $20.99PeakForce Labs
- Median 10mg cost
- $53.99One normalized offer per vendor
- Lowest package total
- $10.80Novaglo Research · package size may differ
- Public COA coverage
- 98%166 of 169 vendors
What the market shows
PeptidePrices found 219 in-stock listings from 169 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 61% below the vendor median of $53.99; 83 vendors (49%) fall below that median. 166 of 169 vendors (98%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is TB-500? Research, safety, and status
TB-500 is a lab-made peptide fragment built from the active part of thymosin beta-4 (Tβ4), a protein found throughout the body, thymus, spleen, lungs, brain, heart, that plays a central role in tissue repair, cellular regeneration, and wound healing. It's studied mostly for soft-tissue and tendon recovery and is popular with athletes and biohackers chasing faster injury repair.
The honest framing up front: the encouraging results are largely preclinical (animal models) or come from trials on the full thymosin beta-4 protein rather than the TB-500 fragment itself. There are no large human trials for the musculoskeletal uses people actually buy it for. It's not FDA-approved and it's banned in sport. Everything below is research context, not medical advice.
Key research takeaways
Its core mechanism is binding G-actin to reorganize the cell's cytoskeleton, that's what lets cells migrate to injury sites, alongside anti-inflammatory effects, new blood-vessel growth, and stem/progenitor-cell mobilization.
Most human-relevant data is on the parent protein (thymosin beta-4), not the TB-500 fragment, and is concentrated in wound-healing and cardiac/eye trials. Musculoskeletal use in humans is essentially anecdotal.
It is not FDA-approved, is flagged by the FDA as a substance with safety concerns (barred from 503A/503B compounding), and is sold only on the unregulated research-chemical market.
It's banned in sport, WADA lists thymosin beta-4 and its derivatives under S2 (growth factors), prohibited in and out of competition, explicitly named since the 2018 list.
TB-500 at a glance
PeptidePrices safety rating
6/10 · Not FDA-approved
Mechanism
Upregulates actin, promotes cell migration and proliferation, inhibits inflammatory cytokines (IL-6, TNF-α), stimulates angiogenesis and neurogenesis.
Research areas
Injury recovery (muscle, tendon, ligament); anti-inflammatory; cardiac repair; neuroprotection; hair growth; systemic healing agent.
Regulatory / research status
Research / preclinical only
Half-life
~2-3 days.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Head rush/fatigue immediately post-injection; possible nausea; theoretical concern re: cancer proliferation (avoid with active malignancy).
Parent protein TB4 has Phase II data; fragment widely used anecdotally; proangiogenic concern theoretical Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Promotes cardiac repair by activating integrin-linked kinase (ILK) in epicardial progenitor cells, mobilizing them to regenerate damaged myocardium after MI.
- Phase 1 RCT in healthy volunteers (2010) confirmed IV thymosin β4 was safe and well-tolerated, clearing a key hurdle for clinical development.
- Neuroprotective in multiple stroke and TBI models: improves neurological scores, reduces infarct size, and promotes white matter remodeling when administered post-injury.
- Accelerates wound healing via actin sequestration and anti-inflammatory cytokine modulation, Phase 2 ophthalmic RCT confirmed benefit in dry eye disease.
Selected references
- Thymosin Beta-4: A Multi-Functional Regenerative Peptide · Expert Opinion on Biological Therapy, 2012
- Randomized Controlled Trial of IV Thymosin Beta-4 in Healthy Volunteers · Annals of the New York Academy of Sciences, 2010
- Dose Response of Thymosin β4 for Acute Stroke · Journal of Neurological Sciences / PMC, 2014
- Thymosin Beta-4 Accelerates Wound Healing · Journal of Investigative Dermatology, 1999
- Function and Application of Thymosin β4 in Tissue Repair · IJMS / PMC, 2021
- Thymosin Beta-4 Activates ILK, Promotes Cardiac Repair · Nature, 2004
Research products are not for human use. Looking for clinician-supervised care instead? Compare licensed US telehealth programs that may offer provider-guided peptide protocols when clinically appropriate.
Compare supervised options →Related pages