Epitalon (Epithalon, sequence Ala-Glu-Asp-Gly) is a synthetic tetrapeptide based on the natural pineal peptide epithalamin, developed by Russian researcher Vladimir Khavinson and studied for over 35 years.
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Where to buy Epithalon: 125 vendors compared
| Vendor | Price | Actions |
|---|---|---|
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Tracked every day
Epithalon listing prices, tracked daily
The five cheapest in-stock package prices for Epithalon on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$19.79
- 2nd cheapest$19.99
- 3rd cheapest$20.00
- 4th cheapest$23.39
- 5th cheapest$24.00
Vendors most often in the cheapest five
- IDUN Peptides22 days$19.990.0%
- Pure Peptides UK18 days$23.390.0%
- Alpha Peptides18 days$26.32last seen Oct 6, 20260.0%
- Real Peptides16 days$24.000.0%
- Evolve Peptides13 days$25.00last seen Oct 7, 20260.0%
- Puratek Peptides4 days$26.95last seen Sep 24, 20260.0%
- Corix Labs3 days$19.790.0%
- Ararat Peptides3 days$20.000.0%
Top 8 of 13 vendors that reached the cheapest five
Current market data
Epithalon Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Epithalon is $17.99 from IDUN Peptides. The median across vendors is $37.99.
- Lowest 10mg cost
- $17.99IDUN Peptides
- Median 10mg cost
- $37.99One normalized offer per vendor
- Lowest package total
- $17.99IDUN Peptides · package size may differ
- Public COA coverage
- 98%122 of 125 vendors
What the market shows
PeptidePrices found 167 in-stock listings from 125 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 53% below the vendor median of $37.99; 62 vendors (50%) fall below that median. 122 of 125 vendors (98%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Epithalon? Research, safety, and status
Epitalon is a four-amino-acid peptide modeled on epithalamin, a regulatory peptide from the pineal gland. It is the most-studied compound in the 'bioregulator' tradition pioneered by Vladimir Khavinson, researched primarily for anti-aging via telomere maintenance and circadian/melatonin support.
It is investigational outside Russia, not FDA-approved, and everything below is research context rather than medical guidance.
Key research takeaways
Its headline mechanism is telomerase activation, reported at extraordinarily low concentrations (10⁻¹⁷-10⁻¹⁵ M), alongside pineal/melatonin regulation and epigenetic gene-expression effects.
Most evidence is cell-culture and animal work plus decades of Russian clinical use; it is not FDA-approved. A theoretical telomerase/cancer concern is the key caution.
Epithalon at a glance
PeptidePrices safety rating
7/10 · Not FDA-approved
Mechanism
Stimulates telomerase activity, lengthening telomeres; regulates melatonin production via pineal gland; antioxidant; modulates neuroendocrine function; restores circadian rhythms.
Research areas
Anti-aging / longevity; telomere extension; improved sleep; immune enhancement; antioxidant; cancer prevention (animal data); neuroendocrine regulation.
Regulatory / research status
Research / preclinical only
Half-life
~30 minutes.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Generally very well-tolerated. Long-term human safety data limited but decades of Russian research show safety.
Russian clinical studies in elderly patients showed safety; telomerase activation; theoretical cancer concern unproven Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Synthetic tetrapeptide (Ala-Glu-Asp-Gly) derived from epithalamin that induces telomerase activity and elongates telomeres in human somatic cells, a potential molecular mechanism of lifespan extension.
- Extends mean and maximum lifespan in Drosophila and mice; regulates melatonin-to-cortisol ratio in aged primates, supporting its role in circadian and neuroendocrine aging.
- Inhibits mammary tumor formation in HER-2/neu transgenic mice and stimulates neurogenesis-related gene expression, indicating broad anti-aging biological activity beyond telomere maintenance.
Selected references
- Overview of Epitalon, the Pineal Tetrapeptide · IJMS / PMC, 2025
- Epithalon Induces Telomerase Activity and Telomere Elongation in Human Cells · Bulletin of Experimental Biology & Medicine, 2003
- Peptide Promotes Overcoming of Hayflick Limit in Human Somatic Cells · Bulletin of Experimental Biology & Medicine, 2004
- Effect of AEDG Peptide on Telomere Length · Bulletin of Experimental Biology & Medicine, 2019
- AEDG (Epitalon) Stimulates Gene Expression in Neurogenesis Pathways · Molecules / PMC, 2020
- Epitalon Increases Lifespan in Drosophila melanogaster · Mechanisms of Ageing and Development, 2000
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