Retatrutide Price Comparison — Compare 30 Vendors

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GLP-1 / metabolic researchSafety Rating 7/10

Price Comparison

Compare vendors · per 10mg

30 vendors competing

VendorPrice$ / mgUpdated
Alpha Peptides8/10$125.99$139.99−10% · code PEPTIDEPRICES10$2.52Jun 12, 2026Buy →
Puratek Peptides9.5/10$103.45$114.95−10% · code PEPTIDEPRICES$2.59May 19, 2026Buy →
Red River Peptides6/10$53.55$63.00−15% · code PEPTIDEPRICES$2.68May 19, 2026Buy →
Peptyx Labs8.5/10$100.00$125.00−20% · code PEPTIDEPRICES25$3.33May 26, 2026Buy →
Arizen Bio Labs6.5/10$179.99$199.99−10% · code PEPTIDEP10$3.60Jun 21, 2026Buy →
Glacier Aminos9.5/10$202.49$224.99−10% · code peptidep$4.05Jun 23, 2026Buy →

Research details

Retatrutide — research data

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range2–12 mg SC weekly (Phase 3 target doses)source ↗
AdministrationSubcutaneous injection
Half-life~6 days (estimated from Phase 2 PK)
Safety7/10 · Not FDA-approved (Phase III)
NCAA D1Not listed

Overview

About Retatrutide

Mechanism of action

Triple agonist of GLP-1, GIP, and glucagon receptors. Combines appetite suppression, improved insulin sensitivity, and increased energy expenditure.

Safety profile

Nausea, vomiting, diarrhea, reduced appetite, potential cardiovascular effects; still in clinical trials — full profile not established. · Phase II showed strong efficacy/tolerability; GI side effects; novel mechanism; promising safety data

Storage

Stability & handling

❄️Lyophilized (powder)−20°C24+ months
💉Reconstituted2–8°C~30 days
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Safety & Interactions

Contraindications & Drug Interactions

Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.

⚠ CriticalContraindication

Personal or family history of MTC (by class effect — applies across GLP-1/GIP/Glucagon agonists).

⚠ CriticalContraindication

MEN 2 syndrome.

⚠ CriticalInteraction

Other GLP-1 agonists (Semaglutide, Tirzepatide) — do not combine.

Sources: NEJM

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A beginner's guide to Retatrutide — the triple-agonist peptide making headlines in obesity research.

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Research

Studies & key findings

  • Phase 2 NEJM trial demonstrated up to 24.2% mean body weight reduction at 48 weeks — the highest reported for any investigational anti-obesity agent at the time.
  • TRIUMPH-4 Phase 3 topline (Eli Lilly, Dec 2025) reported ~28.7% average body weight reduction at 68 weeks in adults with obesity and knee osteoarthritis; TRANSCEND-T2D-1 topline (Mar 2026) showed ~−2.0% HbA1c and ~16.8% weight reduction in type 2 diabetes.

17 peer-reviewed sources cited — clinical, preclinical, and regulatory.

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