Cortagen is the tetrapeptide Ala-Glu-Asp-Pro from Vladimir Khavinson's group. It differs from Epitalon (Ala-Glu-Asp-Gly) by one amino acid at the end.
Cortagen Prices
9 vendors · 0 with an issuer-verified COA · lowest 10mg from $44.99 · checked
Where to buy Cortagen: 9 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| $44.99 | Buy Cortagen from MS Peptides | |
| $45.00 | Buy Cortagen from Atomik Labz | |
| $47.19 | Buy Cortagen from Cenexa Labs | |
| $50.99 | Buy Cortagen from Orbitrex Peptides | |
| $50.99 | Buy Cortagen from Synthesis Peptides | |
| $55.24 | Buy Cortagen from SomaChems | |
| $60.1220mg packageChecked today | Buy Cortagen from Regenix Peptides | |
| $60.1420mg packageChecked today | Buy Cortagen from Kensington Labs | |
| $62.97 | Buy Cortagen from BioLongevity Labs |
Tracked every day
Cortagen listing prices, tracked daily
The five cheapest in-stock package prices for Cortagen on each collected day, and the vendors that most often held those places.
No collected listings for this compound yet.
Current market data
Cortagen Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Cortagen is $44.99 from MS Peptides. The median across vendors is $50.99.
- Lowest 10mg cost
- $44.99MS Peptides
- Median 10mg cost
- $50.99One normalized offer per vendor
- Lowest package total
- $44.99MS Peptides · package size may differ
- Public COA coverage
- 100%9 of 9 vendors
What the market shows
PeptidePrices found 9 in-stock listings from 9 vendors, checked through Oct 8, 2026. The lowest 10mg cost is 12% below the vendor median of $50.99; 3 vendors (33%) fall below that median. 9 of 9 vendors (100%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Cortagen? Research, safety, and status
Cortagen is four amino acids: alanine, glutamic acid, aspartic acid, proline. It shares the Ala-Glu-Asp core with Cartalax (AED) and Epitalon (AEDG). The proline at the end is the only difference from Epitalon.
The developers group it with Vilon, Epitalon and Livagen as synthetic "cytogens." In a 2001 rat explant study each one stimulated growth of the tissue its parent extract came from, and Cortagen's was brain cortex.
Key research takeaways
The developers say it was designed from an amino acid analysis of Cortexin, a cattle brain-cortex extract registered in Russia as a nootropic drug. When the same group later went looking for short peptides inside its brain-cortex extract by mass spectrometry, it reported finding Pinealon (Glu-Asp-Arg), not AEDP.
The only human data is a 35-patient example inside a US patent, with 15 people on Cortagen and no statistics in the text.
At least two papers report Cortagen doing nothing where its sister peptides worked, one of them from Khavinson's own co-authors. Vendor pages rarely mention them.
Cortagen at a glance
PeptidePrices safety rating
6/10 · Not FDA-approved
Mechanism
Synthetic tetrapeptide designed from the brain-cortex extract Cortexin; animal studies report effects on gene expression and free-radical processes.
Research areas
Brain and nervous-system bioregulator research. Human clinical benefit is not established.
Regulatory / research status
Research / preclinical only
Half-life
Not established in direct human pharmacokinetic studies.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Human safety data is sparse. The available evidence is mainly preclinical and small Russian studies from one research group, and it does not establish clinical efficacy.
Russian bioregulator; short peptide; limited but clean data. Human evidence is thin and mostly from one research group. Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Cortagen is the tetrapeptide Ala-Glu-Asp-Pro from Vladimir Khavinson's group. It differs from Epitalon (Ala-Glu-Asp-Gly) by one amino acid at the end.
- The developers say it was designed from an amino acid analysis of Cortexin, a cattle brain-cortex extract registered in Russia as a nootropic drug. When the same group later went looking for short peptides inside its brain-cortex extract by mass spectrometry, it reported finding Pinealon (Glu-Asp-Arg), not AEDP.
- The best-known result is a rat sciatic nerve study: 27% faster fiber growth and 40% faster conduction after 10 days of injections. It has not been reproduced by an unconnected lab that we could find.
- The only human data is a 35-patient example inside a US patent, with 15 people on Cortagen and no statistics in the text.
Selected references
- Tetrapeptide stimulating functional activity of neurons, pharmacological agent based thereon and method of use thereof · patents.google.com, 1999
- Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray · PubMed, 2004
- RLS Encyclopedia (rlsnet.ru) site search for "кортаген," no drug or supplement entry returned · rlsnet.ru
- ClinicalTrials.gov search for "cortagen," no matching trials · clinicaltrials.gov
- Cortexin (Кортексин), official prescribing information as reproduced on medi.ru; registration Р N003862/02; manufacturers GEROPHARM and Firma Ferment · medi.ru
- [Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds] · PubMed, 2008
Related pages