PeptidePrices safety rating
6/10 · Not FDA-approved
Humanin Prices
4 vendors · 2 with an issuer-verified COA · lowest 10mg from $57.74 · checked
Where to buy Humanin: 4 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| $57.74 | Buy Humanin from Swift Peptides | |
| $60.1410mg packageChecked today | Buy Humanin from Kensington Labs | |
| 3-test panelVerified COAKovera Labs · Tested Aug 13, 2026 | $111.0010mg packageChecked today | Buy Humanin from Pure Peptides |
| 6-test panelVerified COABioSyn Systems · Tested Oct 20, 2025 | $119.99 | Buy Humanin from Cenexa Labs |
Tracked every day
Humanin listing prices, tracked daily
The five cheapest in-stock package prices for Humanin on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$60.14
- 2nd cheapest$65.00
- 3rd cheapest$76.99
- 4th cheapest$111.00
- 5th cheapest$149.99
Vendors most often in the cheapest five
- Swift Peptides22 days$76.990.0%
- Kensington Labs18 days$60.14-50.1%
- American Peptides14 days$150.00last seen Oct 4, 20260.0%
- Cenexa Labs8 days$149.99last seen Oct 8, 20260.0%
- Pure Peptides6 days$111.00+70.8%
Current market data
Humanin Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Humanin is $57.74 from Swift Peptides. The median across vendors is $85.57.
- Lowest 10mg cost
- $57.74Swift Peptides
- Median 10mg cost
- $85.57One normalized offer per vendor
- Lowest package total
- $57.74Swift Peptides · package size may differ
- Public COA coverage
- 100%4 of 4 vendors
What the market shows
PeptidePrices found 5 in-stock listings from 4 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 33% below the vendor median of $85.57; 2 vendors (50%) fall below that median. 4 of 4 vendors (100%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Humanin? Research, safety, and status
Humanin at a glance
Mechanism
Mitochondria-derived peptide (MTDP); binds FPRL1/Bax; anti-apoptotic; neuroprotective against Alzheimer's-related toxicity; activates STAT3 and AMPK; insulin sensitizing.
Research areas
Neuroprotection (Alzheimer's, cognitive decline); anti-aging / longevity; insulin sensitivity; cardiovascular protection; mitochondrial health.
Regulatory / research status
Research / preclinical only
Half-life
~2-3 hours.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Very limited human data. Generally well-tolerated in early research. Long-term safety profile not established.
Endogenous peptide; cytoprotective; animal studies favorable; no proven harms Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Humanin is a 21-amino-acid peptide encoded within the mitochondrial 16S rRNA region and first identified in 2001 as a neuroprotective factor from surviving neurons in Alzheimer's disease brains; circulating humanin levels decline with age across species, and children of human centenarians show substantially elevated humanin compared to age-matched controls.
- Mechanistically, humanin binds IGFBP-3 and blocks amyloid-beta aggregation; in the presence of IGFBP-3 the protective interaction with Aβ is abolished and amyloid oligomer formation increases, identifying IGFBP-3 as a physiological regulator of humanin's neuroprotective capacity and a potential Alzheimer's disease risk modifier.
- Humanin activates chaperone-mediated autophagy (CMA) by enhancing substrate-binding and lysosomal translocation via HSP90 interaction, and also triggers ERK1/2, AKT, and STAT3 signaling pathways, providing mechanistic underpinning for its cardioprotective, neuroprotective, and metabolic effects.
- Astrocytes release humanin to protect hippocampal neurons from glutamate-induced synaptic damage; ovarian hormone loss reduces hippocampal humanin expression, providing a potential molecular link between menopause-related estrogen decline and accelerated cognitive aging.
Selected references
- The mitochondrial derived peptide humanin is a regulator of lifespan and healthspan · Aging (Albany NY), 2020
- Humanin Prevents Age-Related Cognitive Decline in Mice and is Associated with Improved Cognitive Age in Humans · Sci Rep, 2018
- Humanin Blocks the Aggregation of Amyloid-β Induced by Acetylcholinesterase, an Effect Abolished in the Presence of IGFBP-3 · Biochemistry, 2020
- Humanin is an endogenous activator of chaperone-mediated autophagy · J Cell Biol, 2018
- Humanin, a Mitochondrial-Derived Peptide Released by Astrocytes, Prevents Synapse Loss in Hippocampal Neurons · Front Aging Neurosci, 2019
- Humanin attenuates Alzheimer-like cognitive deficits and pathological changes induced by amyloid β-peptide in rats · Neurosci Bull, 2014
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