PNC-27Anti-CancerSafety Rating 5/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
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Overview
About PNC-27
Mechanism of action
Synthetic peptide containing p53 activation domain fused to penetratin cell-penetrating sequence; selectively inserts into membranes of cancer cells (which overexpress HDM2); induces apoptosis in cancer cells while leaving normal cells unharmed.
Safety profile
Limited human data. Animal studies show selective cancer cell killing with minimal normal cell toxicity. Long-term safety profile not established. · Experimental; designed for cancer cell selectivity; limited data; no proven harms
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