PTD-DBMTissue RepairSafety Rating 6/10

Primary research areaHair loss treatment (androgenic alopecia)

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose rangeResearch compound. Animal/early human protocols: 1 mg SC or intradermal at scalp, several times weekly. Topical formulations also under investigation.
AdministrationInjection / Topical
Safety6/10 · Not FDA-approved
NCAA D1Not listed

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Overview

About PTD-DBM

Mechanism of action

Cell-penetrating peptide that disrupts the Axin-LRP5/6 interaction; activates Wnt/β-catenin signaling pathway; promotes hair follicle neogenesis and stem cell activation; regenerates dermal papilla cells.

Safety profile

Limited human data. Theoretical concerns with systemic Wnt activation (oncogenic pathway); localized application minimizes risk. Generally well-tolerated in limited studies. · Promotes osteogenesis in animals; no human safety data but no adverse signals

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