Price Comparison
PE-22-28
cognitive
6 of 6 vendors
| Vendor | Price | 10mg cost | Updated | Actions |
|---|---|---|---|---|
| CertaPeptides 7.5/10 COA ✓Ships: InternationalPayment not verified Verification & shipping7.5/10 COA ✓Ships: InternationalPayment not verified | $34.1610mg package | $34.16Checked jun 27, 2026 | Jun 27, 2026 | Buy PE-22-28 from CertaPeptides |
| Nationwide Peptides 6/10 COA ✓Ships: USCredit/debit card Verification & shipping6/10 COA ✓Ships: USCredit/debit card | $39.60 | $39.60Checked aug 5, 2026 | Aug 5, 2026 | Buy PE-22-28 from Nationwide Peptides |
| Mile High Compounds 9.5/10 COA ✓Ships: United States, US territories, Aruba, Canada, Denmark, El Salvador, France, Puerto Rico, and United KingdomCredit/debit card · Bank transfer Verification & shipping9.5/10 COA ✓Ships: United States, US territories, Aruba, Canada, Denmark, El Salvador, France, Puerto Rico, and United KingdomCredit/debit card · Bank transfer | $44.99 | $44.99Checked aug 3, 2026 | Aug 3, 2026 | Buy PE-22-28 from Mile High Compounds |
| MS Peptides 8/10 COA ✓Ships: US + internationalCredit/debit card · ACH Verification & shipping8/10 COA ✓Ships: US + internationalCredit/debit card · ACH | $44.99 | $44.99Checked aug 19, 2026 | Aug 19, 2026 | Buy PE-22-28 from MS Peptides |
| SomaChems 8.5/10 COA ✓Ships: USCredit card · eCheck Verification & shipping8.5/10 COA ✓Ships: USCredit card · eCheck | $63.74 | $63.74Checked may 14, 2026 | May 14, 2026 | Buy PE-22-28 from SomaChems |
| Atomik Labz 7/10 COA ✓Ships: US + CanadaPayment not verified Verification & shipping7/10 COA ✓Ships: US + CanadaPayment not verified | $45.00 | $90.00Checked aug 4, 2026 | Aug 4, 2026 | Buy PE-22-28 from Atomik Labz |
Research details
PE-22-28 — research data
Half-lifeNot well-established. Likely requires daily dosing.
Regulatory statusNot FDA-approved
NCAA D1Not listed
Overview
About PE-22-28
Mechanism of action
Optimized analogue of spadin; selective TREK-1 (K2P potassium channel) blocker; activates serotonergic neurotransmission; antidepressant effects via BDNF upregulation; fast-acting.
Safety profile
Very limited human data. Well-tolerated in animal studies. Theoretical serotonergic side effects. · Spadin analog; TREK-1 inhibitor; animal data favorable; no proven harms; early stage
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