GonadorelinHormone TherapySafety Rating 8/10

Primary research areaTRT adjunct (preserve testicular size/fertility)

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range100 mcg SC 2–3x/week (TRT preservation) or pulsatile dosing 100 mcg every 90 min via pump for fertility protocols.
AdministrationVaries
Safety8/10 · FDA-approved (Factrel)
NCAA D1Banned

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Overview

About Gonadorelin

Mechanism of action

Synthetic GnRH; binds pituitary GnRH receptors; stimulates pulsatile LH and FSH release; preserves testicular function and fertility during TRT/steroid use.

Safety profile

Injection site reactions; headache; nausea; rare hypersensitivity. Desensitization with continuous (non-pulsatile) dosing. · Diagnostic and therapeutic use; headache, flushing; short-acting; well-characterized

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