Follistatin-344Growth Factor ModulatorSafety Rating 5/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Price Comparison
Compare vendors · per 1mg
| Vendor | Price | $ / mg | Updated | |
|---|---|---|---|---|
| SomaChemsBest $/mgCOA ✓ · 3P | $79.99 | $79.99 | May 14, 2026 | Buy → |
| PureRawzCOA ✓ · 3P | $132.12 | $132.12 | May 14, 2026 | Buy → |
| Core PeptidesCOA ✓ · 3P | $138.00 | $138.00 | Apr 16, 2026 | Buy → |
| Swiss ChemsCOA ✓ · 3P | $152.95 | $152.95 | Apr 17, 2026 | Buy → $25 off $100+·auto |
| Biotech PeptidesCOA unknown | $162.00 | $162.00 | May 14, 2026 | Buy → |
Overview
About Follistatin-344
Mechanism of action
Endogenous glycoprotein; binds and inhibits activin and myostatin; reduces myostatin-mediated muscle growth inhibition; promotes satellite cell activation and muscle fiber hypertrophy.
Safety profile
Significant risk: unregulated muscle growth, organ growth, cardiovascular strain; limited human safety data; potential cancer promotion via activin inhibition. · Limited human data; no proven major harms; theoretical concerns about uncontrolled growth unconfirmed
Storage
Stability & handling
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Research
Studies & key findings
- Follistatin directly binds and neutralizes myostatin with a high-affinity Kd of ~5.84 × 10⁻¹⁰ M; the full follistatin protein is required for binding, and follistatin dose-dependently rescued muscle cell differentiation blocked by myostatin by restoring expression of Pax-3 and MyoD in chick developmental models.
- A Phase 1/2a clinical trial delivered follistatin via AAV1 intramuscular injection to six Becker muscular dystrophy patients; results showed improved 6-minute walk test scores (up to +125 m in some patients), reduced fibrosis, decreased central nucleation, and enlarged muscle fiber cross-sectional area at higher doses, with no serious adverse events.