IGF-1 LR3 is a synthetic, more-potent analog of insulin-like growth factor-1, it has NEVER been approved for human use anywhere, and there have been ZERO human clinical trials.
IGF-1 LR3 Prices
94 vendors · 40 with an issuer-verified COA · lowest 1mg from $36.54 · checked
Where to buy IGF-1 LR3: 94 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| $36.54 | Buy IGF-1 LR3 from Red River Peptides | |
| $41.40 | Buy IGF-1 LR3 from Peptide Giants | |
| 4-test panelVerified COAILS Laboratories · Tested Aug 12, 2026 | $45.00 | Buy IGF-1 LR3 from American Amino & Peptides |
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| $46.811mg packageChecked today | Buy IGF-1 LR3 from Kensington Labs | |
| 5-test panelVerified COAILS Laboratories · Tested Jun 28, 2026 | $49.49 | Buy IGF-1 LR3 from Studz Peptides |
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| 3-test panelVerified COAFreedom Diagnostics · Tested May 3, 2026 | $52.25 | Buy IGF-1 LR3 from Elytra Labs |
| 1-test panelVerified COAILS Laboratories | $52.49 | Buy IGF-1 LR3 from Amino Club |
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| 3-test panelVerified COABioViridian · Tested Jul 27, 2026 | $53.99 | Buy IGF-1 LR3 from RUO Market |
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| 3-test panelCOA on fileJanoshik · Tested Sep 19, 2025 · Client sales@molipeptide.com | $65.30 | Buy IGF-1 LR3 from PhaseOne AUS |
| 2-test panelCOA on fileMarfleet Analytical Services · Tested Jul 15, 2026 | $65.481mg packageChecked today | Buy IGF-1 LR3 from Pure Peptides UK |
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| 3-test panelVerified COAFreedom Diagnostics · Tested Oct 7, 2025 | $67.14 | Buy IGF-1 LR3 from Synthesis Peptides |
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| 6-test panelVerified COAILS Laboratories · Tested Jul 16, 2026 | $67.49 | Buy IGF-1 LR3 from VoidResearch |
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| 3-test panelVerified COAFreedom Diagnostics · Tested Aug 17, 2026 | $69.991mg packageChecked today | Buy IGF-1 LR3 from BioNova Peptides |
| 7-test panelVerified COAKovera Labs | $72.00 | Buy IGF-1 LR3 from Instant Peptides |
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| $150.001mg packageChecked Jul 31 | Buy IGF-1 LR3 from Apex Peptides | |
| $175.001mg packageChecked today | Buy IGF-1 LR3 from Legion Peptides | |
| $960.00 | Buy IGF-1 LR3 from Veragen Labs |
Tracked every day
IGF-1 LR3 listing prices, tracked daily
The five cheapest in-stock package prices for IGF-1 LR3 on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$13.36
- 2nd cheapest$23.99
- 3rd cheapest$24.00
- 4th cheapest$25.00
- 5th cheapest$26.00
Vendors most often in the cheapest five
- Happy Peptides22 days$24.000.0%
- Nationwide Peptides22 days$26.000.0%
- Peptide Giants19 days$46.00last seen Oct 9, 20260.0%
- Pure Peptides UK18 days$13.360.0%
- VAYN11 days$38.00last seen Sep 30, 20260.0%
- American Amino & Peptides4 days$25.000.0%
- Kensington Labs4 days$46.81last seen Oct 6, 20260.0%
- Red River Peptides2 days$42.99last seen Oct 5, 20260.0%
Top 8 of 10 vendors that reached the cheapest five
Current market data
IGF-1 LR3 Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 1mg cost for IGF-1 LR3 is $36.54 from Red River Peptides. The median across vendors is $71.00.
- Lowest 1mg cost
- $36.54Red River Peptides
- Median 1mg cost
- $71.00One normalized offer per vendor
- Lowest package total
- $13.36Pure Peptides UK · package size may differ
- Public COA coverage
- 98%92 of 94 vendors
What the market shows
PeptidePrices found 99 in-stock listings from 94 vendors, checked through Oct 10, 2026. The lowest 1mg cost is 49% below the vendor median of $71.00; 47 vendors (50%) fall below that median. 92 of 94 vendors (98%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 1mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is IGF-1 LR3? Research, safety, and status
IGF-1 LR3 (Long R3 IGF-1) is an 83-amino-acid engineered version of IGF-1 designed to circulate longer and act more potently than the native hormone. It sits downstream of the GH axis as the effector, where HGH stimulates IGF-1, IGF-1 LR3 IS the IGF-1 signal, amplified.
This profile is deliberately safety-forward: there are no human trials, the preclinical record includes animal deaths, and the compound is strictly a research chemical. Everything below is research context, not medical guidance.
Key research takeaways
An N-terminal extension and an R3 substitution reduce its binding to IGF-binding proteins, leaving more free, active hormone and giving a long ~20-30 hour half-life, roughly 3× the potency of native IGF-1.
The safety record is unusually alarming for the preclinical literature: documented animal deaths from prolonged hypoglycemia, plus species-dependent and even paradoxical (growth-inhibiting) responses. Human response is genuinely unknown.
It carries a real cancer-proliferation concern (elevated IGF-1 is epidemiologically linked to several cancers) and is WADA-prohibited. Strictly a research chemical.
IGF-1 LR3 at a glance
PeptidePrices safety rating
3/10 · Not FDA-approved (never tested in humans)
Mechanism
Analogue of IGF-1 with arginine substitution at position 3 and N-terminal extension; binds IGF-1 receptors; promotes muscle cell hyperplasia and hypertrophy; inhibits apoptosis; enhances nutrient uptake.
Research areas
Muscle hypertrophy and hyperplasia; body composition; athletic performance; anti-catabolic; GH axis optimization.
Regulatory / research status
Research / preclinical only
Half-life
~20-30 hours (LR3 modification extends vs. native IGF-1).
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Documented animal DEATHS from prolonged (20-30h) hypoglycemia; severe acute hypoglycemia risk; cancer-proliferation concern (IGF-1 epidemiologically linked to several cancers); zero human trials; species-paradoxical responses. WADA-banned. Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Long R3 modification (Arg substitution at position 3 + 13-aa N-terminal extension) reduces IGF-binding protein (IGFBP) affinity by >95%, extending half-life from ~10 min to 20-30 hours.
- Demonstrated superior anabolic potency vs native IGF-1 in dexamethasone-treated catabolic rat models, supporting use in muscle-wasting and recovery contexts.
- Systemic infusion stimulates growth of multiple organs and lean mass; shows plaque-stabilizing effects in atherosclerosis models by promoting smooth muscle cell survival.
Selected references
- IGF-I Variants with Reduced IGFBP Binding Are Anabolic in Dexamethasone-Treated Rats · Biochemical Journal, 1992
- Superior Potency of IGF-I Analogues That Bind Poorly to IGFBPs · Journal of Endocrinology, 1996
- IGF-1 Plaque-Stabilizing Effects in Atherosclerosis · American Journal of Pathology, 2011
- Long R3 IGF-I Infusion Stimulates Organ Growth in Hypophysectomized Rats · Journal of Endocrinology, 1995
- Mohan & Baylink, Insulin-Like Growth Factors in Bone · PubMed, 2002
Related pages
