TriptorelinHormone TherapySafety Rating 8/10

Primary research areaPCT (post-cycle therapy) — single-shot LH restart

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose rangePCT: 100 mcg SC single injection followed by SERM therapy. Medical: 3.75 mg depot monthly. Pulsatile vs. continuous = opposite hormonal effects.
AdministrationInjection
Safety8/10 · FDA-approved (Trelstar)
NCAA D1Banned

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Overview

About Triptorelin

Mechanism of action

Potent GnRH agonist; initial stimulation then desensitization/downregulation of pituitary GnRH receptors; with pulsatile use causes LH/FSH/testosterone surge; continuous use causes chemical castration.

Safety profile

PCT use: temporary testosterone spike, possible E2 surge, then reset. Continuous: hot flashes, testosterone suppression, bone loss. Depot: castration-level testosterone. · Approved for prostate cancer; standard GnRH agonist profile; well-established

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