Testosterone CypionateHormone TherapySafety Rating 3/10

Primary research areaTestosterone replacement therapy (TRT)

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose rangeTRT: 100–200 mg IM or SC every 7–14 days. Performance: 200–600 mg/week. Cypionate ester allows weekly or biweekly injection.
AdministrationInjection
Safety3/10 · FDA-approved (Depo-Testosterone)
NCAA D1Banned

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Overview

About Testosterone Cypionate

Mechanism of action

Esterified exogenous testosterone; converted to active testosterone after ester cleavage; binds androgen receptors; promotes protein synthesis, nitrogen retention, red blood cell production, muscle hypertrophy, and libido.

Safety profile

Testicular atrophy, infertility (suppresses natural testosterone), polycythemia, cardiovascular risk (lipid changes), injection site pain, acne, hair loss, gynecomastia (via aromatization), mood changes. · Schedule III controlled substance; cardiovascular risks; polycythemia; liver toxicity at high doses; hormonal suppression

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