PramlintideWeight LossSafety Rating 8/10

Primary research areaAdjunct therapy for type 1 and 2 diabetes

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range15-60 mcg before meals (T1D); 60-120 mcg before meals (T2D)
AdministrationSubcutaneous injection
Safety8/10 · FDA-approved (Symlin)
NCAA D1Not listed

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Overview

About Pramlintide

Mechanism of action

Amylin analog; slows gastric emptying, reduces glucagon, increases satiety

Safety profile

Nausea, hypoglycemia when combined with insulin · Approved for diabetes; hypoglycemia risk (black box); nausea; requires careful dosing but manageable

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