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Research details
Plecanatide — research data
Regulatory statusFDA-approved (Trulance)
NCAA D1Not listed
Overview
About Plecanatide
Mechanism of action
Guanylate cyclase-C agonist (uroguanylin analog); increases intestinal fluid secretion and transit
Safety profile
Diarrhea; dehydration and serious adverse events in young children · Approved for IBS-C/CIC; diarrhea main SE; well-characterized
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