PlecanatideFDA ApprovedSafety Rating 8/10
Primary research areaChronic idiopathic constipation
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Research dose range3 mg once daily
AdministrationOral tablet
Safety8/10 · FDA-approved (Trulance)
NCAA D1Not listed
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Overview
About Plecanatide
Mechanism of action
Guanylate cyclase-C agonist (uroguanylin analog); increases intestinal fluid secretion and transit
Safety profile
Diarrhea; dehydration and serious adverse events in young children · Approved for IBS-C/CIC; diarrhea main SE; well-characterized
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