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Research details
Pasireotide — research data
Regulatory statusFDA-approved (Signifor)
NCAA D1Not listed
Overview
About Pasireotide
Mechanism of action
Multi-receptor somatostatin analog (SSTR1/2/3/5); suppresses ACTH from pituitary corticotrophs
Safety profile
Hyperglycemia (major concern), GI effects, bradycardia, cholelithiasis · Approved for Cushing's; hyperglycemia common (expected with mechanism); GI side effects
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