Orexin AWeight LossSafety Rating 6/10

Primary research areaNarcolepsy

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose rangeResearch compound. Intranasal: 200–2000 mcg. SC/IV protocols under investigation.
AdministrationInjection / Intranasal
Safety6/10 · Not FDA-approved
NCAA D1Not listed

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VendorPrice$ / mgUpdated
PureRawzBest $/mgCOA ✓ · 3P$95.62$19.12May 14, 2026Buy →
Behemoth LabzCOA ✓ · 3P$96.63$19.33May 14, 2026Buy →

Overview

About Orexin A

Mechanism of action

Endogenous neuropeptide produced in hypothalamus; binds OX1R and OX2R; promotes wakefulness and arousal; regulates energy homeostasis, appetite, and reward pathways.

Safety profile

Limited human data. Potential: anxiety, appetite changes, cardiovascular effects. Intranasal generally well-tolerated in studies. · Endogenous neuropeptide; limited human data; cardiovascular effects in animals; no proven major harms

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