NesiritideCardiovascularSafety Rating 8/10
Primary research areaAcute decompensated congestive heart failure
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Research dose range2 mcg/kg IV bolus then 0.01 mcg/kg/min infusion
AdministrationIntravenous
Safety8/10 · FDA-approved (Natrecor)
NCAA D1Not listed
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Overview
About Nesiritide
Mechanism of action
Recombinant human BNP; vasodilation and natriuresis via cGMP signaling
Safety profile
Hypotension, renal function concerns; limited current use · Approved for acute HF; hypotension risk; renal concerns debated; fell out of favor clinically
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