PeptidePrices safety rating
6/10 · Not FDA-approved
MGF Prices
7 vendors · 2 with an issuer-verified COA · lowest 10mg from $107.96 · checked
Where to buy MGF: 7 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| $107.96 | Buy MGF from Cenexa Labs | |
| $120.002 × 5mg packages · 10mg totalChecked today | Buy MGF from Pure Peptides | |
| $133.655 × 2mg packages · 10mg totalChecked today | Buy MGF from Regenix Peptides | |
| 2-test panelVerified COAOptima Labs | $139.955 × 2mg packages · 10mg totalChecked Oct 7 | Buy MGF from Peptides Lab UK |
| $195.005 × 2mg packages · 10mg totalChecked today | Buy MGF from Alpha Carbon Labs | |
| 2-test panelVerified COAJanoshik · Tested Aug 19, 2026 | $224.96 | Buy MGF from ZestyRat Research |
| $242.25 | Buy MGF from Paramount Peptides |
Tracked every day
MGF listing prices, tracked daily
The five cheapest in-stock package prices for MGF on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$26.73
- 2nd cheapest$39.00
- 3rd cheapest$39.00
- 4th cheapest$60.00
- 5th cheapest$127.50
Vendors most often in the cheapest five
- Alpha Carbon Labs21 days$39.000.0%
- Regenix Peptides15 days$26.730.0%
- Cenexa Labs8 days$26.99last seen Oct 8, 20260.0%
- Paramount Peptides7 days$127.500.0%
- Pure Peptides4 days$60.00+53.8%
- Peptides Lab UK2 days$27.99last seen Oct 7, 20260.0%
Current market data
MGF Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for MGF is $107.96 from Cenexa Labs. The median across vendors is $139.95.
- Lowest 10mg cost
- $107.96Cenexa Labs
- Median 10mg cost
- $139.95One normalized offer per vendor
- Lowest package total
- $21.59Cenexa Labs · package size may differ
- Public COA coverage
- 100%7 of 7 vendors
What the market shows
PeptidePrices found 8 in-stock listings from 7 vendors, checked through Oct 9, 2026. The lowest 10mg cost is 23% below the vendor median of $139.95; 3 vendors (43%) fall below that median. 7 of 7 vendors (100%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is MGF? Research, safety, and status
MGF at a glance
Mechanism
Alternatively spliced isoform of IGF-1 (Ec peptide); released in response to mechanical load/muscle damage; activates and proliferates satellite (muscle stem) cells; distinct from systemic IGF-1, acts locally at damage site; does not bind IGFBPs.
Research areas
Muscle repair after training; satellite cell activation; hypertrophy; injury recovery; anabolic post-workout signaling. Best used immediately post-exercise for local muscle repair.
Regulatory / research status
Research / preclinical only
Half-life
~Minutes (native MGF is rapidly degraded without PEGylation). Must inject immediately post-workout.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Rapid degradation limits systemic effects vs. PEG-MGF.
IGF-1 splice variant; limited data; localized action; no proven major harms in available studies Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- MGF is generated by alternative splicing of the IGF-1 gene in mechanically stressed skeletal muscle; the splice variant produces an E-domain peptide that acts transiently and locally to activate muscle satellite cells, initiating a proliferative burst before longer-lived IGF-1Ea drives terminal differentiation.
- Exercise-induced muscle damage in humans produces a rapid, transient upregulation of MGF mRNA within hours of eccentric contraction, with the synthetic MGF E peptide activating signaling pathways independent of the classic IGF-1 receptor, suggesting a distinct paracrine mechanism.
- Age-related failure to upregulate MGF after mechanical overload, demonstrated in older rat muscle, is proposed as a key driver of sarcopenia; older muscles showed markedly lower MGF expression and failed to upregulate IGF-1 receptor or MyoD following the same stimulus that robustly activated young muscle.
- A rigorously controlled 2014 study found that synthetic MGF C-terminal peptide (24-AA) up to 500 ng/mL failed to stimulate proliferation, differentiation signaling, or Akt/ERK pathways in primary human myoblasts or C2C12 cells, raising questions about reproducibility of earlier in vitro findings.
Selected references
- Minireview: Mechano-growth factor: a putative product of IGF-I gene expression involved in tissue repair and regeneration · Endocrinology, 2010
- MGF E peptide (MGF-E) activates human muscle progenitor cells and induces an increase in their fusion potential at different ages · Mech Ageing Dev, 2011
- Age-related loss of skeletal muscle function and the inability to express MGF in response to mechanical overload · FEBS Lett, 2001
- Expression of IGF-1 isoforms after exercise-induced muscle damage in humans: characterization of the MGF E peptide actions in vitro · In Vivo, 2009
- Mechano-growth factor peptide has no apparent effect on myoblasts or primary muscle stem cells · Am J Physiol Endocrinol Metab, 2014
- MGF promotes proliferation and inhibits differentiation of porcine satellite cells by down-regulation of myogenic transcriptional factors · Mol Cell Biochem, 2012
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