Price Comparison
MGF
Growth Factor Analog Peptide
2 of 2 vendors
| Vendor | Price | 10mg cost | Updated | Actions |
|---|---|---|---|---|
| Alpha Peptides 8/10 COA ✓Ships: USCredit/debit card Verification & shipping8/10 COA ✓Ships: USCredit/debit card | $23.26 | $116.30Checked jul 31, 2026 | Jul 31, 2026 | Buy MGF from Alpha Peptides |
| Nationwide Peptides 6/10 COA ✓Ships: USCredit/debit card Verification & shipping6/10 COA ✓Ships: USCredit/debit card | $27.90 | $139.50Checked aug 5, 2026 | Aug 5, 2026 | Buy MGF from Nationwide Peptides |
Research details
MGF — research data
Half-life~Minutes (native MGF is rapidly degraded without PEGylation). Must inject immediately post-workout.
Regulatory statusNot FDA-approved
NCAA D1Banned
Overview
About MGF
Mechanism of action
Alternatively spliced isoform of IGF-1 (Ec peptide); released in response to mechanical load/muscle damage; activates and proliferates satellite (muscle stem) cells; distinct from systemic IGF-1 — acts locally at damage site; does not bind IGFBPs.
Safety profile
Hypoglycemia risk, water retention, injection site reactions. Rapid degradation limits systemic effects vs. PEG-MGF. · IGF-1 splice variant; limited data; localized action; no proven major harms in available studies
Storage
Stability & handling
Lyophilized (powder)−20°Clong-term stable
Reconstituted2–8°Cwithin 14–30 days
Related pages
More on MGF
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Research
Studies & key findings
- MGF is generated by alternative splicing of the IGF-1 gene in mechanically stressed skeletal muscle; the splice variant produces an E-domain peptide that acts transiently and locally to activate muscle satellite cells, initiating a proliferative burst before longer-lived IGF-1Ea drives terminal differentiation.
- Exercise-induced muscle damage in humans produces a rapid, transient upregulation of MGF mRNA within hours of eccentric contraction, with the synthetic MGF E peptide activating signaling pathways independent of the classic IGF-1 receptor, suggesting a distinct paracrine mechanism.