Mazdutide (IBI362 / LY3305677) is a dual GLP-1 + glucagon receptor agonist, an oxyntomodulin analog. It's a different dual-agonist than GLP-2T (which is GLP-1/GIP): mazdutide pairs GLP-1 appetite suppression with glucagon-driven thermogenesis and hepatic fat metabolism.
Mazdutide Prices
14 vendors · 5 with an issuer-verified COA · lowest 10mg from $60.00 · checked
Where to buy Mazdutide: 14 vendors compared
| Vendor | Price | Actions |
|---|---|---|
| 3-test panelVerified COAFreedom Diagnostics | $60.0010mg packageChecked today | Buy Mazdutide from Pro Research Peptide |
| $66.8410mg packageChecked today | Buy Mazdutide from Kensington Labs | |
| 4-test panelVerified COAFreedom Diagnostics · Tested Jul 24, 2026 | $70.0010mg packageChecked Aug 1 | Buy Mazdutide from PeakForm Peptides |
| $87.99 | Buy Mazdutide from Vital Core Research | |
| $90.74 | Buy Mazdutide from Swift Peptides | |
| 3-test panelVerified COAChromate | $96.90 | Buy Mazdutide from Happy Peptides |
| Verified COAChromate | $97.20 | Buy Mazdutide from Pantheon Peptides |
| $135.00 | Buy Mazdutide from Hydro Research | |
| $135.00 | Buy Mazdutide from Nationwide Peptides | |
| $135.0010mg packageChecked today | Buy Mazdutide from Alpha Carbon Labs | |
| $143.99 | Buy Mazdutide from Cenexa Labs | |
| $144.50 | Buy Mazdutide from Sparta Labs | |
| $187.00 | Buy Mazdutide from Optima Supply | |
| 2-test panelVerified COAOptima Labs | $199.9910mg packageChecked today | Buy Mazdutide from Peptides Lab UK |
Tracked every day
Mazdutide listing prices, tracked daily
The five cheapest in-stock package prices for Mazdutide on each collected day, and the vendors that most often held those places.
Five cheapest in-stock package prices per day
Listed package price before coupons, any vial size. This is not the coupon-adjusted lowest 10mg price used to rank the comparison.
- Cheapest$60.00
- 2nd cheapest$66.84
- 3rd cheapest$72.00
- 4th cheapest$75.00
- 5th cheapest$100.00
Vendors most often in the cheapest five
- Nationwide Peptides22 days$75.000.0%
- Sparta Labs21 days$100.000.0%
- Pro Research Peptide18 days$60.000.0%
- Kensington Labs18 days$66.84-23.2%
- Pantheon Peptides16 days$72.000.0%
- Vital Core Research5 days$109.99last seen Sep 24, 20260.0%
- Optima Supply2 days$110.00last seen Sep 22, 20260.0%
- Happy Peptides2 days$114.00last seen Sep 22, 20260.0%
Top 8 of 9 vendors that reached the cheapest five
Current market data
Mazdutide Price Report
A current summary of public listings after the price comparison above. Shipping and tax are not included.
The lowest current 10mg cost for Mazdutide is $60.00 from Pro Research Peptide. The median across vendors is $116.10.
- Lowest 10mg cost
- $60.00Pro Research Peptide
- Median 10mg cost
- $116.10One normalized offer per vendor
- Lowest package total
- $60.00Pro Research Peptide · package size may differ
- Public COA coverage
- 93%13 of 14 vendors
What the market shows
PeptidePrices found 16 in-stock listings from 14 vendors, checked through Oct 10, 2026. The lowest 10mg cost is 48% below the vendor median of $116.10; 7 vendors (50%) fall below that median. 13 of 14 vendors (93%) publish public COA evidence.
A public COA link shows that a vendor publishes testing data. It does not prove that every listed vial has a matching current report. Match the product, strength, batch, and lot before relying on a report.
How this report is calculated
The headline and median use each vendor's lowest whole-package checkout cost to obtain at least 10mg. Smaller packages are multiplied until the target is met, while larger packages retain their full checkout price. The lowest package total is shown only as secondary context because package sizes differ. Known public coupon discounts are applied. Shipping, tax, and unverified promotions are excluded.
Research context
What is Mazdutide? Research, safety, and status
It is not FDA-approved, and several of the figures below are company-reported/topline, flagged where that's the case. Everything here is research context, not medical guidance.
Key research takeaways
Mechanistically it fills the GLP-1/glucagon slot in the incretin landscape (GLP-1S = GLP-1; GLP-2T = GLP-1/GIP; GLP-3R = triple agonist; survodutide = also GLP-1/glucagon).
It is not FDA-approved and is developed by Innovent/Lilly, with most trials run in Chinese populations.
Mazdutide at a glance
PeptidePrices safety rating
7/10 · Not FDA-approved (Phase III)
Mechanism
Dual GLP-1 receptor and glucagon receptor (GCGR) agonist; GLP-1 component suppresses appetite and improves glycemia; glucagon component increases energy expenditure, promotes lipolysis, and reduces hepatic fat; weekly injection.
Research areas
Obesity / weight loss; NAFLD/NASH (hepatic fat reduction); type 2 diabetes; metabolic syndrome; Chinese Phase III trials showing significant weight loss.
Regulatory / research status
Research / preclinical only
Half-life
~7 days.
Storage
Lyophilized vial: store at -20°C long-term or 2-8°C short-term, protected from light.
Reported side effects
Nausea, vomiting, diarrhea, decreased appetite; still in trials.
Phase III trials ongoing; GI side effects; dual agonist; promising efficacy and tolerability Safety ratings summarize published clinical data, adverse-event reporting, and regulatory status. How PeptidePrices rates evidence. Research information only, not medical advice.
Study highlights
- Mazdutide (IBI362 / LY3305677) is a dual GLP-1 + glucagon receptor agonist, an oxyntomodulin analog, distinct from GLP-2T (GIP/GLP-1). The glucagon arm adds thermogenesis/energy expenditure on top of GLP-1 appetite suppression.
- Reported Phase 3 results (GLORY program, Innovent/Lilly, largely Chinese cohorts) describe up to ~20% weight loss at 9 mg over 60 weeks, but these figures are company/topline-stage and should be confirmed against the primary publications before being treated as established.
- It occupies the GLP-1/glucagon niche in the incretin landscape (vs GLP-1S GLP-1-only, GLP-2T GLP-1/GIP, GLP-3R triple-agonist).
- It is not FDA-approved.
Selected references
- GLORY-1 / GLORY-2 Phase 3 Topline (company-reported, VERIFY against primary publication) · Innovent / Eli Lilly, 2025
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