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Research details

Linaclotide — research data

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range72-290 mcg once daily
AdministrationOral capsule
Safety8/10 · FDA-approved (Linzess)
NCAA D1Not listed

Overview

About Linaclotide

Mechanism of action

Guanylate cyclase-C agonist guanylin peptide analog; accelerates GI transit and fluid secretion

Safety profile

Diarrhea, abdominal pain; pediatric boxed warning · Approved for IBS-C/CIC; diarrhea most common; well-characterized safety

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