Linaclotide0 vendors competing
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Research details
Linaclotide — research data
Regulatory statusFDA-approved (Linzess)
NCAA D1Not listed
Overview
About Linaclotide
Mechanism of action
Guanylate cyclase-C agonist guanylin peptide analog; accelerates GI transit and fluid secretion
Safety profile
Diarrhea, abdominal pain; pediatric boxed warning · Approved for IBS-C/CIC; diarrhea most common; well-characterized safety
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