LeuprolideHormone TherapySafety Rating 8/10

Primary research areaProstate cancer

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range1 mg/day SC or 7.5-45 mg depot IM monthly
AdministrationSubcutaneous or IM injection
Safety8/10 · FDA-approved (Lupron)
NCAA D1Banned

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Overview

About Leuprolide

Mechanism of action

GnRH receptor agonist; initial stimulation then desensitization and sex hormone suppression

Safety profile

Hot flashes, bone density loss, depression, sexual dysfunction · Decades of safe use; hot flashes, bone loss expected; injection site reactions; well-established

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