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Research details

Enfuvirtide — research data

Regulatory statusFDA-approved (Fuzeon)
NCAA D1Permitted

Overview

About Enfuvirtide

Mechanism of action

Fusion inhibitor T-20 peptide; prevents HIV envelope gp41 hairpin formation and cell membrane fusion

Safety profile

Injection site reactions nearly universal, bacterial pneumonia; rarely used today · Approved for HIV; injection site reactions in 98% (local, not systemic); hypersensitivity rare

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