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Research details
Daptomycin — research data
Regulatory statusFDA-approved (Cubicin)
NCAA D1Permitted
Overview
About Daptomycin
Mechanism of action
Cyclic lipopeptide antibiotic; calcium-dependent membrane insertion disrupts bacterial membrane potential
Safety profile
Myopathy (monitor CPK weekly), eosinophilic pneumonia, GI effects · Approved for serious infections; monitor CPK; eosinophilic pneumonia rare; well-characterized
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