BivalirudinCardiovascularSafety Rating 9/10

Primary research areaAnticoagulation in PCI

Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.

Research dose range0.75 mg/kg bolus then 1.75 mg/kg/h infusion
AdministrationIntravenous
Safety9/10 · FDA-approved (Angiomax)
NCAA D1Not listed

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Overview

About Bivalirudin

Mechanism of action

Direct thrombin inhibitor hirudin analog; binds both free and clot-bound thrombin reversibly

Safety profile

Bleeding, back pain, hypotension, bradycardia · Extensive clinical use; predictable pharmacokinetics; manageable bleeding risk

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