Side-by-side comparison

TB-500 vs Thymosin Alpha-1 — Price & Profile Comparison

TB-500

Cellular PeptideSafety 6/10

Tissue repair research

vs

Thymosin Alpha-1

Cellular PeptideSafety 8/10

Immune-modulation research

TB-500
Thymosin Alpha-1
Cheapest price
$28.19 /10mg
$37.50 /10mg
Vendors stocking
29
24
Safety rating
6/10
8/10
Mol. weight
4,963 Da
3,108.3 g/mol
Administration
Subcutaneous injection
Subcutaneous injection

The short answer

TB-500 vs Thymosin Alpha-1: which to choose

TB-500 is the cheaper option — roughly $28 vs $38 for the lowest verified listing. TB-500 is the more widely stocked of the two (29 vendors vs 24). Thymosin Alpha-1 carries the higher safety rating (8/10 vs 6/10). Both are cellular peptide compounds, so the decision usually comes down to price, evidence, and tolerability rather than use case.

Price Comparison — 2026

TB-500

VendorPrice
Alpha Peptides$28.19 /10mgBuy →
Woosh Labs$35.99 /10mgBuy →
Averix Labs$35.99 /10mgBuy →
Midwest Peptide$44.99 /10mgBuy →
Ascension Peptides$50.00 /10mgBuy →
Glacier Aminos$53.09 /10mgBuy →

Thymosin Alpha-1

VendorPrice
Ascension Peptides$37.50 /10mgBuy →
Optimum Formula$40.49 /10mgBuy →
Hydro Research$52.00 /10mgBuy →
Glacier Aminos$57.59 /10mgBuy →
Amino Club$63.98 /10mgBuy →

Vendors Carrying Both

17 vendors stock both TB-500 and Thymosin Alpha-1 — convenient if you want to bundle an order.

Ascension PeptidesTB-500: $50.00Thymosin Alpha-1: $37.50Visit →
Hydro ResearchTB-500: $72.00Thymosin Alpha-1: $52.00Visit →
Glacier AminosTB-500: $53.09Thymosin Alpha-1: $57.59Visit →
GLP-1 Research LabTB-500: $70.00Thymosin Alpha-1: $60.00Visit →
Amino ClubTB-500: $63.98Thymosin Alpha-1: $63.98Visit →
Polar PeptidesTB-500: $70.19Thymosin Alpha-1: $64.79Visit →
Optima SupplyTB-500: $65.00Thymosin Alpha-1: $65.00Visit →
SomaChemsTB-500: $71.98Thymosin Alpha-1: $79.98Visit →
Modern AminosTB-500: $76.00Thymosin Alpha-1: $88.00Visit →
Apex Peptide SupplyTB-500: $59.99Thymosin Alpha-1: $89.99Visit →
Woosh LabsTB-500: $35.99Thymosin Alpha-1: $89.99Visit →
Pinnacle Peptide LabsTB-500: $84.98Thymosin Alpha-1: $93.49Visit →
CertaPeptidesTB-500: $83.81Thymosin Alpha-1: $99.95Visit →
Liv Pure WellnessTB-500: $110.00Thymosin Alpha-1: $110.00Visit →
LeoLab RxTB-500: $160.00Thymosin Alpha-1: $120.00Visit →
BioLongevity LabsTB-500: $164.97Thymosin Alpha-1: $129.97Visit →
Core PeptidesTB-500: $140.00Thymosin Alpha-1: $149.00Visit →

Safety Notes

TB-500

FDA: Not FDA-approved

Parent protein TB4 has Phase II data; fragment widely used anecdotally; proangiogenic concern theoretical

Thymosin Alpha-1

FDA: Approved in 30+ countries

11,000+ patients in 30+ trials; well-tolerated; approved as Zadaxin globally; excellent safety record

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