Side-by-side comparison
TB-500 vs GHK-Cu — Price & Profile Comparison
TB-500
Cellular PeptideSafety 6/10Tissue repair research
GHK-Cu
Dermal CompoundSafety 8/10Skin / wound healing research
The short answer
TB-500 vs GHK-Cu: which to choose
GHK-Cu is the cheaper option — roughly $2 vs $28 for the lowest verified listing. GHK-Cu is the more widely stocked of the two (38 vendors vs 29). GHK-Cu carries the higher safety rating (8/10 vs 6/10). They target different goals — TB-500 is a cellular peptide compound while GHK-Cu is a dermal compound one — so they're often complementary rather than direct substitutes.
Price Comparison — 2026
TB-500
GHK-Cu
Vendors Carrying Both
29 vendors stock both TB-500 and GHK-Cu — convenient if you want to bundle an order.
Safety Notes
TB-500
FDA: Not FDA-approved
Parent protein TB4 has Phase II data; fragment widely used anecdotally; proangiogenic concern theoretical
GHK-Cu
FDA: Not FDA-approved (cosmetic)
Extensive topical safety; naturally occurring peptide; well-tolerated across all routes studied
