Side-by-side comparison
Melanotan-2 vs PT-141 — Price & Profile Comparison
Melanotan-2
Melanocortin PeptideSafety 3/10Melanocortin research
PT-141
Melanocortin PeptideSafety 8/10Melanocortin / sexual research
The short answer
Melanotan-2 vs PT-141: which to choose
On price they're close — about $20 vs $20 for the cheapest COA-verified listing. Melanotan-2 is the more widely stocked of the two (31 vendors vs 24). PT-141 carries the higher safety rating (8/10 vs 3/10). Both are melanocortin peptide compounds, so the decision usually comes down to price, evidence, and tolerability rather than use case.
Price Comparison — 2026
Melanotan-2
PT-141
Vendors Carrying Both
19 vendors stock both Melanotan-2 and PT-141 — convenient if you want to bundle an order.
Safety Notes
Melanotan-2
FDA: Not FDA-approved
Documented serious harms: peer-reviewed melanoma/eruptive-nevi case reports with formal MHRA and TGA safety warnings, plus priapism (a urological emergency). Directly stimulates melanocytes. Nausea and flushing are common.
PT-141
FDA: FDA-approved (Vyleesi)
FDA-approved for HSDD; nausea common (40%); transient BP increase; limited to 1 dose/24hr
Explore Further
Melanotan-2