Price Comparison
Melanotan-2
| Vendor | Price | 10mg cost | Updated | Actions |
|---|---|---|---|---|
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| Alpha Peptides 8/10 COA ✓Ships: USCredit/debit card Verification & shipping8/10 COA ✓Ships: USCredit/debit card | $21.05 | $21.05Checked jul 31, 2026 | Jul 31, 2026 | Buy Melanotan-2 from Alpha Peptides |
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| NextGen Peptides 8/10 COA ✓Ships: USVisa · American Express Verification & shipping8/10 COA ✓Ships: USVisa · American Express | $22.49 | $22.49Checked jul 24, 2026 | Jul 24, 2026 | Buy Melanotan-2 from NextGen Peptides |
| Amino Club 10/10 COA ✓Ships: US + internationalVisa · American Express Verification & shipping10/10 COA ✓Ships: US + internationalVisa · American Express | $22.74 | $22.74Checked aug 7, 2026 | Aug 7, 2026 | Buy Melanotan-2 from Amino Club |
Research details
Melanotan-2 — research data
Overview
About Melanotan-2
Mechanism of action
Non-selective melanocortin agonist (MC1R, MC3R, MC4R); stimulates melanin production; activates MC4R for potent sexual arousal; significantly more sexual effect than MT-1.
Safety profile
Nausea, facial flushing, fatigue, spontaneous erections, increased libido, yawning, hyperpigmentation, mole changes (monitor), potential cancer promotion concerns. · Documented serious harms: peer-reviewed melanoma/eruptive-nevi case reports with formal MHRA and TGA safety warnings, plus priapism (a urological emergency). Directly stimulates melanocytes. Nausea and flushing are common.
Storage
Stability & handling
Safety & Interactions
Contraindications & Drug Interactions
Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.
Personal or family history of melanoma or atypical nevi — melanocortin agonists darken moles; theoretical melanoma risk debated but unproven.
Priapism (prolonged painful erection) — reported in literature. Emergency medical evaluation required if erection lasts >4 hours.
Rhabdomyolysis — case reports of muscle breakdown with high doses.
Related pages
More on Melanotan-2
Stack & Compare
Frequently Researched Together
Research
Studies & key findings
- Synthetic cyclic α-MSH analog that binds MC1R, MC3R, MC4R and MC5R — the broad receptor profile is what drives both the tanning response (MC1R → tyrosinase → eumelanin) and the central pro-erectile/anorexic effects (MC4R in the hypothalamus), and is also why side effects cluster across so many systems.
- Originally developed at the University of Arizona in the 1980s for UV-sparing skin photoprotection in patients at high melanoma risk; Dorr et al. 1996 (Life Sciences) showed dose-dependent tanning in a Phase I trial, and Wessells 1998 (J Urology) demonstrated improved erections in men with psychogenic erectile dysfunction.