MOTS-c
| Vendor | Price | 10mg cost | Updated | Actions |
|---|---|---|---|---|
| Anglo Peptides 7.5/10 COA on requestShips: CanadaVisa / American Express / Discover · Interac e-Transfer Verification & shipping7.5/10 COA on requestShips: CanadaVisa / American Express / Discover · Interac e-Transfer | $23.65 | $23.65Checked jul 19, 2026 | Jul 19, 2026 | Buy MOTS-c from Anglo Peptides |
| Cielo Peptides 6/10 COA ✓Ships: Shipping destinations not verifiedCredit/debit card · Venmo Verification & shipping6/10 COA ✓Ships: Shipping destinations not verifiedCredit/debit card · Venmo | $24.00 | $24.00Checked aug 8, 2026 | Aug 8, 2026 | Buy MOTS-c from Cielo Peptides |
| Amino Club 10/10 COA ✓Ships: US + internationalVisa · American Express Verification & shipping10/10 COA ✓Ships: US + internationalVisa · American Express | $25.99 | $25.99Checked aug 7, 2026 | Aug 7, 2026 | Buy MOTS-c from Amino Club |
| Puratek Peptides 7/10 COA ✓Ships: USZelle · Cash App Verification & shipping7/10 COA ✓Ships: USZelle · Cash App | $26.96 | $26.96Checked jul 31, 2026 | Jul 31, 2026 | Buy MOTS-c from Puratek Peptides |
| Lost Coast Aminos 9.5/10 COA ✓Ships: USCredit/debit card · Zelle Verification & shipping9.5/10 COA ✓Ships: USCredit/debit card · Zelle | $27.00 | $27.00Checked 6 days ago | 6 days ago | Buy MOTS-c from Lost Coast Aminos |
| TrustedPeps 8.5/10 COA ✓Ships: USPayment not verified Verification & shipping8.5/10 COA ✓Ships: USPayment not verified | $27.00 | $27.00Checked aug 1, 2026 | Aug 1, 2026 | Buy MOTS-c from TrustedPeps |
Research details
MOTS-c — research data
Overview
About MOTS-c
Mechanism of action
Mitochondria-derived peptide encoded in the 12S rRNA gene; activates AMPK; improves insulin sensitivity; enhances mitochondrial biogenesis; regulates folate cycle and purine metabolism.
Safety profile
Generally well-tolerated in early research. Possible fatigue, injection site reactions. Long-term human data limited. · Endogenous mitochondrial peptide; human study showed safety in metabolic syndrome; promising early data
Storage
Stability & handling
Safety & Interactions
Contraindications & Drug Interactions
Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.
Limited human clinical data; long-term safety unknown.
Research products are not for human use. Looking for clinician-supervised care instead? Compare licensed US telehealth programs that may offer provider-guided peptide protocols when clinically appropriate.
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Frequently Researched Together
Research
Studies & key findings
- Mitochondrial-derived peptide encoded in the 12S rRNA gene; regulates nuclear gene expression from the mitochondria — a paradigm-shifting finding in organelle-to-nucleus communication.
- Exercise-inducible: serum MOTS-c rises after physical activity and mediates improvements in insulin sensitivity and metabolic homeostasis via AMPK activation.