Melanotan-1 (MT-1)Melanocortin PeptideSafety Rating 8/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Price Comparison
Compare vendors · per 10mg
| Vendor | Price | $ / mg | Updated | |
|---|---|---|---|---|
| Ascension PeptidesBest $/mgCOA ✓ · 3P | $20.00 | $2.00 | Apr 16, 2026 | Buy → |
| Amino ClubCOA ✓ · 3P | $23.99 | $2.40 | May 14, 2026 | Buy → |
| Axiom PeptidesCOA on request | $25.00 | $2.50 | Apr 14, 2026 | Buy → |
| Puratek PeptidesCOA ✓ · 3P | $25.16 | $2.52 | May 19, 2026 | Buy → |
| SomaChemsCOA ✓ · 3P | $31.99 | $3.20 | May 14, 2026 | Buy → |
Overview
About Melanotan-1
Mechanism of action
Non-selective melanocortin receptor agonist (MC1R preference); stimulates eumelanin production in melanocytes; photoprotective; FDA-approved for erythropoietic protoporphyria (EPP).
Safety profile
Nausea, facial flushing, fatigue, spontaneous erections. Less sexual side effects than MT-2. Hyperpigmentation, mole changes. · FDA/EMA approved for EPP; nausea, headache mild; selective MC1R agonist; well-studied
Storage
Stability & handling
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Research
Studies & key findings
- FDA-approved as afamelanotide (Scenesse) for erythropoietic protoporphyria (EPP) — the first melanocortin agonist to receive regulatory approval anywhere in the world.
- NEJM Phase 3 RCT (2015) demonstrated a significant increase in pain-free time in sunlight (duration doubled vs placebo) in EPP patients.