IpamorelinGH Secretagogue PeptideSafety Rating 7/10
Research-literature reference data, NOT patient instructions. Not for human use. Consult a licensed clinician for any human application.
Price Comparison
Compare vendors · per 10mg
| Vendor | Price | $ / mg | Updated | |
|---|---|---|---|---|
| Puratek PeptidesBest $/mgCOA ✓ · 3P | $34.16 | $3.42 | May 19, 2026 | Buy → |
| Petratide ScienceCOA ✓ · 3P | $34.95 | $3.50 | May 14, 2026 | Buy → |
| Red River PeptidesCOA ✓ · 3PAvailable on backorder | $21.25 | $4.25 | May 19, 2026 | Buy → |
| Deus MedicalCOA on request | $21.60 | $4.32 | Apr 17, 2026 | Buy → |
| Chameleon PeptidesCOA ✓ · 3P | $46.40 | $4.64 | Apr 17, 2026 | Buy → |
Overview
About Ipamorelin
Mechanism of action
Selective ghrelin/GHS-R1a receptor agonist. Stimulates GH release from pituitary with high selectivity — minimal effect on cortisol, prolactin, or ACTH. Cleanest GHRP.
Safety profile
Generally very well-tolerated. Mild water retention, headache, flushing, hunger. Minimal cortisol/prolactin elevation (advantage over other GHRPs). · Most selective GHRP; minimal cortisol/prolactin; human PK data; widely used with good anecdotal safety
Storage
Stability & handling
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Safety & Interactions
Contraindications & Drug Interactions
Research use only — not medical advice. Consult a licensed physician before using any peptide. Sources are cited where available.
Active malignancy — growth hormone releasers may stimulate tumor growth via IGF-1.
Insulin resistance or Type 2 diabetes — chronic GH elevation worsens insulin sensitivity.
Untreated hypothyroidism — may blunt response.
Related pages
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Ipamorelin Guide
Selective GHRP research guide — how Ipamorelin compares to other secretagogues.
Read full guide · 8 min read →Research
Studies & key findings
- First truly selective GH secretagogue — stimulates pulsatile GH release without affecting cortisol, prolactin, ACTH, or FSH, giving a superior safety profile versus earlier GHRPs.
- British Journal of Pharmacology PK/PD study (1999) characterized human dose-response: a single 1–10 µg/kg IV dose produces dose-proportional GH peaks with rapid washout.