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Side-by-side comparison

Tirzepatide vs Retatrutide — Price & Profile Comparison

Tirzepatide

GIP/GLP-1 PeptideSafety 8/10

Metabolic / weight research

vs

Retatrutide

Triple-Action Metabolic CompoundSafety 7/10

GLP-1 / metabolic research

Tirzepatide
Retatrutide
Cheapest price
$12.75 /10mg
$25.20 /10mg
Vendors stocking
29
35
Safety rating
8/10
7/10
Mol. weight
4,813.45 g/mol
4,731 g/mol
Administration
Subcutaneous injection
Subcutaneous injection

The short answer

Tirzepatide vs Retatrutide: which to choose

Tirzepatide is the cheaper option — roughly $13 vs $25 for the lowest verified listing. Retatrutide is the more widely stocked of the two (35 vendors vs 29). Tirzepatide carries the higher safety rating (8/10 vs 7/10). They target different goals — Tirzepatide is a gip/glp-1 peptide compound while Retatrutide is a triple-action metabolic compound one — so they're often complementary rather than direct substitutes.

Price Comparison — 2026

Tirzepatide

VendorPrice
Alpha Peptides$12.75 /10mgBuy →
Puratek Peptides$13.49 /10mgBuy →
Red River Peptides$15.58 /10mgBuy →
Hydro Research$20.83 /10mgBuy →
Midwest Peptide$27.00 /10mgBuy →
Glacier Aminos$27.60 /10mgBuy →
+23 more vendors →

Retatrutide

VendorPrice
Alpha Peptides$25.20 /10mgBuy →
Puratek Peptides$25.86 /10mgBuy →
Red River Peptides$26.77 /10mgBuy →
Peptyx Labs$33.33 /10mgBuy →
Arizen Bio Labs$36.00 /10mgBuy →
IDUN Peptides$40.49 /10mgBuy →
+29 more vendors →

Vendors Carrying Both

29 vendors stock both Tirzepatide and Retatrutide — convenient if you want to bundle an order.

Alpha PeptidesTirzepatide: $12.75Retatrutide: $25.20Visit →
Puratek PeptidesTirzepatide: $13.49Retatrutide: $25.86Visit →
Red River PeptidesTirzepatide: $15.58Retatrutide: $26.77Visit →
Peptyx LabsTirzepatide: $29.33Retatrutide: $33.33Visit →
Arizen Bio LabsTirzepatide: $49.50Retatrutide: $36.00Visit →
IDUN PeptidesTirzepatide: $31.49Retatrutide: $40.49Visit →
Glacier AminosTirzepatide: $27.60Retatrutide: $40.50Visit →
PepXTirzepatide: $44.55Retatrutide: $41.70Visit →
Hydro ResearchTirzepatide: $20.83Retatrutide: $43.75Visit →
ProminoTirzepatide: $29.70Retatrutide: $48.00Visit →
GLP-1 Research LabTirzepatide: $50.00Retatrutide: $50.00Visit →
Licensed PeptidesTirzepatide: $46.00Retatrutide: $51.66Visit →
Woosh LabsTirzepatide: $71.99Retatrutide: $53.99Visit →
Novatherix LaboratoriesTirzepatide: $54.00Retatrutide: $54.00Visit →
Averix LabsTirzepatide: $33.00Retatrutide: $54.00Visit →
CertaPeptidesTirzepatide: $27.68Retatrutide: $56.59Visit →
Evo Labs ResearchTirzepatide: $42.50Retatrutide: $56.66Visit →
PeptiraTirzepatide: $33.17Retatrutide: $59.67Visit →
Purity PeptidesTirzepatide: $48.42Retatrutide: $60.24Visit →
Midwest PeptideTirzepatide: $27.00Retatrutide: $63.00Visit →
Ignite PeptidesTirzepatide: $50.00Retatrutide: $70.00Visit →
LA PeptidesTirzepatide: $56.66Retatrutide: $76.66Visit →
Evolve PeptidesTirzepatide: $55.24Retatrutide: $78.18Visit →
HolasTirzepatide: $63.00Retatrutide: $81.90Visit →
Pantheon PeptidesTirzepatide: $81.00Retatrutide: $87.48Visit →
Optima SupplyTirzepatide: $43.00Retatrutide: $87.50Visit →
Optimum FormulaTirzepatide: $45.00Retatrutide: $90.00Visit →
Chameleon PeptidesTirzepatide: $32.38Retatrutide: $91.88Visit →
Pinnacle Peptide LabsTirzepatide: $84.99Retatrutide: $127.49Visit →

Safety Notes

Tirzepatide

FDA: FDA-approved (Mounjaro/Zepbound)

Extensive Phase III data; GI side effects manageable; thyroid warning animal-only; strong efficacy

Retatrutide

FDA: Not FDA-approved (Phase III)

Phase II showed strong efficacy/tolerability; GI side effects; novel mechanism; promising safety data

Explore Further

Tirzepatide

Full profile →Cheapest deals →

Retatrutide

Full profile →Cheapest deals →
All current deals →Browse all peptides →
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