Side-by-side comparison
Tesamorelin vs Sermorelin — Price & Profile Comparison
Tesamorelin
Secretagogue PeptideSafety 8/10Visceral fat / lipolysis research
Sermorelin
Secretagogue PeptideSafety 8/10Growth hormone secretagogue research
The short answer
Tesamorelin vs Sermorelin: which to choose
On price they're close — about $39 vs $43 for the cheapest COA-verified listing. Tesamorelin is the more widely stocked of the two (40 vendors vs 25). Both hold the same 8/10 safety rating in our methodology. Both are secretagogue peptide compounds, so the decision usually comes down to price, evidence, and tolerability rather than use case.
Price Comparison — 2026
Tesamorelin
Sermorelin
Vendors Carrying Both
23 vendors stock both Tesamorelin and Sermorelin — convenient if you want to bundle an order.
Safety Notes
Tesamorelin
FDA: FDA-approved (Egrifta)
Approved for HIV lipodystrophy; injection site reactions; fluid retention; well-characterized
Sermorelin
FDA: Previously FDA-approved
Was FDA-approved (discontinued for commercial reasons, not safety); injection site reactions; well-tolerated
Explore Further
Tesamorelin
Sermorelin