Side-by-side comparison
Semaglutide
GLP-1 PeptideSafety 8/10Metabolic / weight research
vs
Tirzepatide
GIP/GLP-1 PeptideSafety 8/10Metabolic / weight research
Semaglutide
Tirzepatide
Cheapest price
$26.25 /5mg
$6.75 /5mg
Vendors stocking
11
13
Safety rating
8/10
8/10
Mol. weight
4,113.58 g/mol
4,813.45 g/mol
Administration
Subcutaneous injection
Subcutaneous injection
Price Comparison — 2026
Semaglutide
VendorPrice
Tirzepatide
VendorPrice
Vendors Carrying Both
8 vendors stock both Semaglutide and Tirzepatide — convenient if you want to bundle an order.
Safety Notes
Semaglutide
FDA: FDA-approved (Ozempic/Wegovy)
Extensive safety data; GI side effects common but manageable; cardiovascular benefit; thyroid warning animal-only
Tirzepatide
FDA: FDA-approved (Mounjaro/Zepbound)
Extensive Phase III data; GI side effects manageable; thyroid warning animal-only; strong efficacy
Explore Further
Semaglutide
Tirzepatide